ArticleHypertension research : official journal of the Japanese Society of Hypertension2015
Early pregnancy waist-to-hip ratio and risk of preeclampsia: a prospective cohort study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Maternal adiposity measures and hypertensive disorders of pregnancy: a meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Association between maternal adiposity measures and adverse maternal outcomes of pregnancy: Systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Evolutionary Theories and Men's Preferences for Women's Waist-to-Hip Ratio: Which Hypotheses Remain? A Systematic Review.Frontiers in psychology · 2019Pooled it
- Waist-to-Hip Ratio versus Body Mass Index as Predictor of Obesity-Related Pregnancy Outcomes.American journal of perinatology · 2016Trial
- Genetic Correlation and Causal Inference Between Female Fat Distribution and Preeclampsia: An Integrative Genomic Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Vascular Assessment Stratifying Preeclampsia Risk in Overweight/Obese Women.Hypertension (Dallas, Tex. : 1979) · 2025Observational
- The effect of maternal pre-pregnancy body mass index on hypertensive disorders of pregnancy (HDP): a systematic review and dose-response meta-analysis of cohort studies involving 50 million pregnancies.EClinicalMedicine · 2025Article
- Influence of Physical Activity Including Squat Exposure on Trunk Muscle Strength and Labour Outcome in Pregnant Women.International journal of exercise science · 2024Article
- Age at Menarche Mediating Visceral Adipose Tissue's Influence on Pre-eclampsia: A Mendelian Randomization Study.The Journal of clinical endocrinology and metabolism · 2023Article
- What is the "cost" of reducing adverse pregnancy outcomes in patients with gestational diabetes mellitus - risk factors for perinatal complications in a retrospective cohort of pregnant women with GDM.BMC pregnancy and childbirth · 2022Article
- Involvement of Receptor for Advanced Glycation Endproducts in Hypertensive Disorders of Pregnancy.International journal of molecular sciences · 2019Article
- The relationship between body mass index and preeclampsia: A systematic review and meta-analysis.International journal of reproductive biomedicine · 2019Review
- Dietary Patterns and The Outcomes of Assisted Reproductive Techniques in Women with Primary Infertility: A Prospective Cohort Study.International journal of fertility & sterility · 2019Article
- Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancys.Clinical science (London, England : 1979) · 2017Article
- From apelin to exercise: emerging therapies for management of hypertension in pregnancy.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Pathophysiology of preeclampsia: an angiogenic imbalance and long-lasting systemic vascular dysfunction.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Epidemiology of hypertensive disorders in pregnancy: prevalence, risk factors, predictors and prognosis.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Article
- Is labor-onset hypertension a novel category among hypertensive disorders of pregnancy associated with adverse events in high-risk subjects? Lights and shadows.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preeclampsia is a major cause of maternal death and morbidity. Body mass index (BMI) predicts an increased risk of developing hypertensive disorders and preeclampsia. However, waist-to-hip ratio (WHR), as a central obesity index, has not been assessed in predicting this disorder in pregnancy. We assumed that WHR might be more sensitive in predicting the risk of preeclampsia, compared with BMI. The aim of this cohort study was to investigate the relationships of BMI and WHR with preeclampsia. This was a prospective cohort study of 1200 pregnant women with singleton pregnancies. Anthropometric indices included WHR and BMI, which were measured at the first antenatal visit (⩽ 12 weeks of gestational age). The incidence of preeclampsia was assessed after 20 weeks of gestation. Maternal demographic data and obstetric outcomes were also recorded for each subject. All of the statistical tests were performed using SPSS software, version 16. The overall incidence of preeclampsia in the study population was 4.2%. The maternal WHR and BMI at the beginning of pregnancy were significantly associated with the occurrence of preeclampsia (P = 0.006 and P = 0.001, respectively). WHR ⩾ 0.85 and BMI ⩾ 25 kg m(-2) in the first 12 weeks of pregnancy had relative risks of 2.317 (confidence interval (CI): 1.26-4.27) and 3.317 (CI: 1.6-6.86) for preeclampsia. BMI and WHR were anthropometric indicators that presented correlations with preeclampsia. Of these anthropometric indices, BMI had greater predictive value in preeclampsia.
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