Evidence map›Paper›PMID 25185821›Full record

ArticleJournal of pediatric urology2014

Resolution rate of isolated low-grade hydronephrosis diagnosed within the first year of life.

Ramiro J Madden-Fuentes, Erin R McNamara, Unwanaobong Nseyo, John S Wiener, Jonathan C Routh, Sherry S Ross

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Antenatally detected urinary tract dilatation: long-term outcome.Pediatric nephrology (Berlin, Germany) · 2023
    Review
  4. Article
  5. Review
  6. Isolated low grade prenatally detected unilateral hydronephrosis: do we need long term follow-up?International braz j urol : official journal of the Brazilian Society of Urology
    Article
  7. 99mTc-DTPA Diuretic Renography with 3 hours late output fraction in the evaluation of hydronephrosis in children.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ramiro J Madden-FuentesDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Erin R McNamaraDepartment of Urology, Boston Children's Hospital, Boston, MA, USA.
Unwanaobong NseyoDivision of Urology, University of California, San Diego, CA, USA.
John S WienerDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Jonathan C RouthDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Sherry S RossDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, NC, USA. Electronic address: sherry.ross@dm.duke.edu.
Duke Medical Center · USBoston Children's Hospital · USDuke University · USUniversity of California San Diego · US

Funding

Duke KURe ProgramK12DK100024 · NIDDK · DUKE UNIVERSITY · PI Cindy Amundsen · 2013 to 2026
$8.4M
Comparative Effectiveness of Vesicoureteral Reflux Treatments in ChildrenK08DK100534 · NIDDK · DUKE UNIVERSITY · PI ROUTH, JONATHAN C · 2014 to 2018
$671k
NIDDK NIH HHS K08 DK100534NIDDK NIH HHS K12 DK100024
6 · The paper itself

Abstract

objectiveDiagnosis of low-grade hydronephrosis often occurs prenatally, during evaluation after urinary tract infection (UTI), or imaging for non-urologic reasons within the first year of life. Its significance in terms of resolution, need for antibiotic prophylaxis, or progression to surgery remains uncertain. We hypothesized that isolated low-grade hydronephrosis in this population frequently resolves, UTIs are infrequent, and progression to surgical intervention is minimal. PATIENTS AND

methodsChildren < 12 months old diagnosed hydronephrosis (Society for Fetal Urology [SFU] grade 1 or 2) between January 2004 and December 2009 were identified by ICD9 code. Patients with other urological abnormalities were excluded. Stability of hydronephrosis, UTI (≥ 100,000 CFU/mL bacterial growth) or need for surgical intervention was noted.

resultsOf 1496 infants with hydronephrosis, 416 (623 renal units) met inclusion criteria. Of 398 renal units with grade 1 hydronephrosis, 385 (96.7%) resolved or remained stable. Only 13 (3.3%) worsened, of which one underwent ureteroneocystostomy. Of 225 renal units with grade 2 hydronephrosis, 222 (98.7%) resolved, improved or remained stable, three (1.3%) worsened, of which one required pyeloplasty. Only 0.7% of patients in the ambulatory setting had a febrile UTI.

conclusionsLow-grade hydronephrosis diagnosed within the first year of life remains stable or improves in 97.4% of renal units. Given the low rate of recurrent UTI in the ambulatory setting, antibiotic prophylaxis has a limited role in management.

Indexed as

Age FactorsAnti-Bacterial AgentsCohort StudiesDisease ProgressionFemaleHumansHydronephrosisInfantInfant, NewbornMaleOutcome Assessment, Health CareSeverity of Illness IndexUrinary Tract InfectionsAnti-Bacterial AgentsHydronephrosisInfantsUrinary tract infection

Identifiers

PMID25185821
PMCPMC4387886
OpenAlexW2135048252

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.