Evidence map›Paper›PMID 25185671›Full record

ArticleEpidemiology and infection2015

Molecular diversity of Scottish Cryptosporidium hominis isolates.

A Deshpande, C L Alexander, M Coyne, S Brownlie, A Smith-Palmer, B L Jones

Abstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A DeshpandeClinical Microbiology,Greater Glasgow and Clyde NHS.
C L AlexanderScottish Microbiology Reference Laboratories,Greater Glasgow and Clyde NHS.
M CoyneScottish Microbiology Reference Laboratories,Greater Glasgow and Clyde NHS.
S BrownlieHealth Protection Scotland,NHS National Services Scotland.
A Smith-PalmerHealth Protection Scotland,NHS National Services Scotland.
B L JonesScottish Microbiology Reference Laboratories,Greater Glasgow and Clyde NHS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium hominis is one of the most prevalent protozoan parasites to infect humans where transmission is via the consumption of infective oocysts. This study describes sporadic cases in addition to the molecular diversity of outbreak cases in Scotland using the glycoprotein-60 subtyping tool. From a total of 187 C. hominis isolates, 65 were subjected to further molecular analysis and 46 were found to be the common IbA10G2 subtype. Unusual subtypes included four isolates belonging to the Ia family (IaA14R3, n = 12; IaA14R2, n = 1; IaA9G3, n = 1; IaA25R3, n = 2), two from the Id family (IdA24, n = 1; IdA17, n = 1) and one belonging to the Ie family, namely IeA11G3T3. These data contribute significantly to our knowledge and understanding of the molecular diversity of C. hominis isolates from outbreak investigations involving Scottish residents which will be beneficial for the management of future outbreaks.

Indexed as

AdolescentAdultAge FactorsChildChild, PreschoolCryptosporidiosisCryptosporidiumDisease OutbreaksFemaleGenetic VariationHumansMaleMiddle AgedScotlandYoung Adultoutbreaks

Identifiers

PMID25185671
PMCPMC9507186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.