ReviewParasitology research2014
Towards identifying novel anti-Eimeria agents: trace elements, vitamins, and plant-based natural products.
Review in Parasitology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 107 citations in OpenAlex.
- Molecular docking and pharmacokinetics of Roweothuria polii compounds with in vivo anti-Eimeria papillata activity.Veterinary research communications · 2025Article
- Effect of Polygain™ Supplementation on Growth Performance, Lesion Severity, and Oocyst Shedding inAnimals : an open access journal from MDPI · 2025Article
- Behavioral and pharmacological effects of phytochemicals inFrontiers in veterinary science · 2025Article
- Therapeutic impact of dietary ginger supplementation in chickens experimentally infected with coccidia-anti-oxidant, biochemical, and pathological evaluations.Frontiers in veterinary science · 2025Article
- Potential Development Ability of Residual Zoites, a Second-Generation Meront, Inducing Long-Term Infection by the Mouse Eimerian Parasite, Eimeria krijgsmanni.Acta parasitologica · 2024Article
- The Anticoccidial In Vitro Effects and Antioxidant Properties of Several Plants Traditionally Used for Coccidiosis in Togo.Veterinary sciences · 2024Article
- Anticoccidial and Antioxidant Activities of an Ethanolic Extract ofVeterinary sciences · 2024Article
- Pharmacological Effects of Biosynthesis Silver Nanoparticles UtilizingInternational journal of nanomedicine · 2024Article
- Effect of anAnimals : an open access journal from MDPI · 2023Article
- Ameliorative Effect of Pomegranate Peel Powder on the Growth Indices, Oocysts Shedding, and Intestinal Health of Broilers under an Experimentally Induced Coccidiosis Condition.Animals : an open access journal from MDPI · 2023Article
- Persea americana extract protects intestinal tissue from Eimeria papillata-induced murine Infection.BMC veterinary research · 2023Article
- Pathogenicity and drug resistance of the Eimeria tenella isolate from Yiwu, Zhejiang province, eastern China.Poultry science · 2023Article
- Biosynthesized Nanosilver from Ginger Extract Exhibits Antioxidant and Hepatic Responses duringACS omega · 2023Article
- In Vitro: The Effects of the Anticoccidial Activities ofMolecules (Basel, Switzerland) · 2023Article
- Influence of Dietary Selenium on the Oxidative Stress in Horses.Biological trace element research · 2023Review
- The Anticoccidial Effect of AlcoholicVeterinary sciences · 2023Article
- Host-mediated beneficial effects of phytochemicals for prevention of avian coccidiosis.Frontiers in immunology · 2023Article
- Biosynthesized selenium nanoparticles to rescue coccidiosis-mediated oxidative stress, apoptosis and inflammation in the jejunum of mice.Frontiers in immunology · 2023Article
- Protective Effect ofAnimals : an open access journal from MDPI · 2022Article
- Transcending Dimensions in Apicomplexan Research: from Two-Dimensional to Three-DimensionalMicrobiology and molecular biology reviews : MMBR · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eimeriosis, a widespread infectious disease of livestock, is caused by coccidian protozoans of the genus Eimeria. These obligate intracellular parasites strike the digestive tract of their hosts and give rise to enormous economic losses, particularly in poultry, ruminants including cattle, and rabbit farming. Vaccination, though a rational prophylactic measure, has not yet been as successful as initially thought. Numerous broad-spectrum anti-coccidial drugs are currently in use for treatment and prophylactic control of eimeriosis. However, increasing concerns about parasite resistance, consumer health, and environmental safety of the commercial drugs warrant efforts to search for novel agents with anti-Eimeria activity. This review summarizes current approaches to prevent and treat eimeriosis such as vaccination and commercial drugs, as well as recent attempts to use dietary antioxidants as novel anti-Eimeria agents. In particular, the trace elements selenium and zinc, the vitamins A and E, and natural products extracted from garlic, barberry, pomegranate, sweet wormwood, and other plants are discussed. Several of these novel anti-Eimeria agents exhibit a protective role against oxidative stress that occurs not only in the intestine of Eimeria-infected animals, but also in their non-parasitized tissues, in particular, in the first-pass organ liver. Currently, it appears to be promising to identify safe combinations of low-cost natural products with high anti-Eimeria efficacy for a potential use as feed supplementation in animal farming.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.