ReviewJournal of endocrinological investigation2014
An update on the medical treatment of Graves' hyperthyroidism.
Review in Journal of endocrinological investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Safety of long-term antithyroid drug treatment? A systematic review.Journal of endocrinological investigation · 2019Pooled it
- Iopanoic acid rapidly restores euthyroidism in refractory thyrotoxicosis pre-thyroidectomy: a retrospective study.European thyroid journal · 2026Review
- Focus on Autoimmune Myocarditis in Graves' Disease: A Case-Based Review.Frontiers in cardiovascular medicine · 2021Review
- Oxidative Stress in Graves Disease and Graves Orbitopathy.European thyroid journal · 2020Article
- Selenium in the Treatment of Graves' Hyperthyroidism and Eye Disease.Frontiers in endocrinology · 2020Review
- The MAGI2 gene polymorphism rs2160322 is associated with Graves' disease but not with Hashimoto's thyroiditis.Journal of endocrinological investigation · 2019Article
- Does Graves' Orbitopathy Ever Disappear? Answers to an Old Question.European thyroid journal · 2017Article
- Emphasis on the early diagnosis of antithyroid drug-induced agranulocytosis: retrospective analysis over 16 years at one Chinese center.Journal of endocrinological investigation · 2017Article
- Graves' orbitopathy, idiopathic orbital inflammatory pseudotumor and Epstein-Barr virus infection: a serological and molecular study.Journal of endocrinological investigation · 2017Article
- Low regulatory T cell and high IL-17 mRNA expression in a mouse Graves' disease model.Journal of endocrinological investigation · 2017Article
- [Autoimmune diseases of the thyroid gland].Der Internist · 2017Review
- Relapse prediction in Graves´ disease: Towards mathematical modeling of clinical, immune and genetic markers.Reviews in endocrine & metabolic disorders · 2016Review
- Management of hyperthyroidism due to Graves' disease: frequently asked questions and answers (if any).Journal of endocrinological investigation · 2016Review
- Pregnancy outcome in women treated with methimazole or propylthiouracil during pregnancy.Journal of endocrinological investigation · 2015Article
- Total thyroid ablation in Graves' orbitopathy.Journal of endocrinological investigation · 2015Review
- Long-term outcome of Graves' orbitopathy following high-dose intravenous glucocorticoids and orbital radiotherapy.Journal of endocrinological investigation · 2015Article
- Elevation of serum creatine kinase during methimazole treatment of Graves disease in a 13-year-old girl and a literature review of similar cases.Annals of pediatric endocrinology & metabolism · 2015Article
- Effects of treatment modalities for Graves' hyperthyroidism on Graves' orbitopathy: a 2015 Italian Society of Endocrinology Consensus Statement.Journal of endocrinological investigation · 2015Article
- Role of genetic and non-genetic factors in the etiology of Graves' disease.Journal of endocrinological investigation · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medical treatment of Graves' hyperthyroidism is based on the use of thionamides; namely, methimazole and propylthiouracil. In the past, methimazole was preferred by European endocrinologists, whereas propylthiouracil was the first choice for the majority of their North American colleagues. However, because of the recent definition of a better side-effect profile, methimazole is nowadays the first choice world while. Although thionamides are quite effective for the short-term control of Graves' hyperthyroidism, a relatively high proportion of patients relapses after thionamide withdrawal. Other possible medical treatments, include iodine and compounds containing iodine, perchlorate, lithium (as an adjuvant in patients undergoing radioiodine therapy), β-adrenergic antagonists, glucocorticoids, and some new molecules still under investigation. Management of Graves' hyperthyroidism using thionamides as well as the other available medical treatments is here reviewed in detail, with a special mention of situations such as pregnancy and lactation, as well as neonatal and fetal thyrotoxicosis.
Indexed as
Identifiers
25185644What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.