Evidence map›Paper›PMID 25185613›Full record

ArticleFemale pelvic medicine & reconstructive surgery

Symptom improvement in women after fecal incontinence treatments: a multicenter cohort study of the pelvic floor disorders network.

Alayne Markland, Lu Wang, J Eric Jelovsek, Linda Brubaker, Ashook Tuteja, Alison C Weidner, Andelka LoSavio, Marlene Corton, Susan Meikle, Holly E Richter

Abstract readMulticenter Study
In one paragraph

Article in Female pelvic medicine & reconstructive surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Alayne MarklandFrom the *Birmingham Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, AL; †Department of Biostatistics, University of Michigan, Ann Arbor, MI; ‡Department of Obstetrics, Gynecology, and Women's Health Institute, Cleveland Clinic, Cleveland, OH; §Department of Obstetrics and Gynecology, Stritch School of Medicine, Loyola University Chicago, Chicago, IL; ∥Department of Medicine, Salt Lake City Veterans Affairs Medical Center, University of Utah, Salt Lake City, UT; ¶Department of Obstetrics and Gynecology, Duke University, Durham, NC; #Department of Medicine, Stritch School of Medicine, Loyola University Chicago, Chicago, IL; **Department of Obstetrics and Gynecology, University of Texas Southwestern, Dallas, TX; ††The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD; and ‡‡Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL.
Lu Wang
J Eric Jelovsek
Linda Brubaker
Ashook Tuteja
Alison C Weidner
Andelka LoSavio
Marlene Corton
Susan Meikle
Holly E Richter
Loyola University Chicago · USUniversity of Alabama at Birmingham · USUniversity of Michigan–Ann Arbor · USBirmingham VA Medical Center · USCleveland Clinic · USDuke University · USUniversity of Utah · US

Funding

Pelvic floor Disorders Network-Data Coordinating CenterU01HD041249 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEI, JOHN T · 2001 to 2010
$19.8M
Pelvic Floor Disorders Network Data Coordinating Center (U01)U01HD069031 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI GANTZ, MARIE G · 2011 to 2015
$19.7M
Perioperative Pelvic Floor Rehab: A Rrandomized TrialU10HD041261 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2001 to 2015
$5.1M
UNC Pelvic Floor Disorders Research CollaborativeU10HD041267 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VISCO, ANTHONY G · 2001 to 2015
$5.0M
The Pelvic Floor Disorders NetworkU10HD041250 · NICHD · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA · 2001 to 2015
$3.8M
Pelvic Floor Disorders NetworkU10HD054214 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LUKACZ, EMILY S. · 2006 to 2015
$3.3M
The Cleveland Clinic Clinical SiteU10HD054215 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI BARBER, MATTHEW D · 2006 to 2015
$3.2M
NICHD Pelvic Floor Disorders Network Clinical Sites (U10)U10HD054241 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI SCHAFFER, JOSEPH I · 2006 to 2015
$1.9M
Pittsburgh Pelvic Floor Research ProgramU10HD069006 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ZYCZYNSKI, HALINA M · 2011 to 2015
$1.6M
UTAH PELVIC FLOOR DISORDERS NETWORKU10HD054136 · NICHD · UNIVERSITY OF UTAH · PI NYGAARD, INGRID E · 2006 to 2015
$1.6M
NICHD NIH HHS U01 HD041249NICHD NIH HHS U01 HD069031NICHD NIH HHS U10 HD041250NICHD NIH HHS U10 HD041261NICHD NIH HHS U10 HD041267NICHD NIH HHS U10 HD054136NICHD NIH HHS U10 HD054214NICHD NIH HHS U10 HD054215NICHD NIH HHS U10 HD054241NICHD NIH HHS U10 HD069006
6 · The paper itself

Abstract

objectivesThe study aims were to characterize women with fecal incontinence (FI) and measure changes in FI severity and quality of life 3 and 12 months after treatment.

methodsThis study is a secondary analysis of a multicenter study measuring adaptive behaviors among women with FI. Women included had a primary complaint of at least monthly FI over 3 consecutive months and planned FI treatment. Demographic and medical history data were obtained at baseline. Data were collected at baseline, 3 months, and 12 months after clinically selected, nonstandardized treatment. Validated questionnaires were as follows: Fecal Incontinence Severity Index, Modified Manchester Health Questionnaire, Pelvic Floor Disorders Inventory's Colorectal and Anal Distress Inventory, Pelvic Floor Impact Questionnaire's Colorectal and Anal Impact Questionnaire, and Medical Outcomes Study Short Form. Questionnaire score changes from baseline were compared using paired t tests at 3 and 12 months after treatment.

resultsOf the 133 women enrolled, 90 women had treatment data at 3 months and 77 at 12 months. Nonsurgical therapies were the most common (78%) with anal sphincter repair in 22%. Fecal Incontinence Severity Index scores and Modified Manchester Health Questionnaire scores significantly improved 3 months after nonsurgical and surgical treatments (-8.8 ± 12.0 and -12.6 ± 19.2, respectively, P < 0.001), as did Colorectal-Anal Distress Inventory and Colorectal-Anal Impact Questionnaire scores (-52.7 ± 70.0 and -60.6 ± 70.0, respectively, P < 0.001) and Medical Outcomes Study Short Form mental health scores (4.2 ± 9.4, P = 0.001). Improvement persisted 12 months posttreatment.

conclusionsIn women seeking care for FI, symptom severity and condition-specific quality of life significantly improve within the first 3 months after FI treatment and are maintained up to 12 months.

Indexed as

Quality of LifeSeverity of Illness IndexAdultAgedAnal CanalDietary FiberExercise TherapyFecal IncontinenceFemaleFollow-Up StudiesHumansMiddle AgedPelvic FloorProspective StudiesSurveys and QuestionnairesTime FactorsDietary Fiber

Identifiers

PMID25185613
PMCPMC4403868
OpenAlexW2054566597

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.