Evidence map›Paper›PMID 25184533›Full record

ReviewAnnual review of genomics and human genetics2014

Emerging issues in public health genomics.

J Scott Roberts, Dana Dolinoy, Beth Tarini

Abstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Service provision of genetics health care in Portugal.Journal of community genetics · 2023
    Article
  10. Review
  11. Review
  12. Integrating Rules for Genomic Research, Clinical Care, Public Health Screening and DTC Testing: Creating Translational Law for Translational Genomics.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2020
    Article
  13. Article
  14. Article
  15. The genetic basis of disease.Essays in biochemistry · 2018
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J Scott RobertsDepartment of Health Behavior & Health Education University of Michigan School of Public Health.
Dana Dolinoy *Department of Environmental Health Sciences University of Michigan School of Public Health.
Beth Tarini *Child Health Evauation & Research Unit Division of Pediatrics University of Michigan Health System.

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STUART A BATTERMAN · 2011 to 2026
$21.3M
Sequencing, Analysis, and Interpretation of SequencingUM1HG006508 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PIENTA, KENNETH J., PIENTA, KENNETH J. · 2013 to 2016
$7.8M
Risk Evaluation and Education for Alzheimer's Disease (REVEAL IV)R01HG002213 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 1999 to 2012
$7.6M
In Utero Exposure to Bisphenol A: Effects on the Fetal EpigenomeR01ES017524 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOLINOY, DANA · 2009 to 2013
$2.2M
Impact of Direct to Consumer Genetic TestingR01HG005092 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C., ROBERTS, SCOTT · 2010 to 2012
$1.1M
Improving Healthcare Delivery for Infants with Positive Newborn Screening ResultsK23HD057994 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TARINI, BETH A · 2009 to 2013
$662k
NHGRI NIH HHS R01 HG002213NHGRI NIH HHS R01 HG005092NHGRI NIH HHS R01HG005092NHGRI NIH HHS R01HG02213NHGRI NIH HHS UM1 HG006508NHGRI NIH HHS UM1HG006508NICHD NIH HHS K23 HD057994NICHD NIH HHS K23HD057994NIEHS NIH HHS ES017524NIEHS NIH HHS P30 ES017885NIEHS NIH HHS R01 ES017524
6 · The paper itself

Abstract

This review highlights emerging areas of interest in public health genomics. First, we describe recent advances in newborn screening (NBS), with a focus on the practice and policy implications of current and future efforts to expand NBS programs (e.g., via next-generation sequencing). Next, we detail research findings from the rapidly progressing field of epigenetics and epigenomics, highlighting ways in which our emerging understanding in these areas could guide future intervention and research efforts in public health. We close by considering various ethical, legal, and social issues posed by recent developments in public health genomics; these include policies to regulate access to personal genomic information, the need to enhance genetic literacy in both health professionals and the public, and challenges in ensuring that the benefits (and burdens) of genomic discoveries and applications are equitably distributed. We also note needs for future genomic research that integrates across basic and social sciences.

Indexed as

High-Throughput Nucleotide SequencingEpigenomicsGenomicsHumansInfant, NewbornNeonatal ScreeningPublic Healthbioethicsepigeneticsepigenomicshealth educationnewborn screening

Identifiers

PMID25184533
PMCPMC4229014

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.