ReviewCold Spring Harbor perspectives in biology2014
Unconventional functions for clathrin, ESCRTs, and other endocytic regulators in the cytoskeleton, cell cycle, nucleus, and beyond: links to human disease.
Review in Cold Spring Harbor perspectives in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Nuclear LC3 Interactome Profiling Identifies Clathrin Heavy Chain as a Mediator of Nuclear LC3 Translocation in Trabecular Meshwork Cells.bioRxiv : the preprint server for biology · 2026Article
- Abscisic acid enhances DNA damage response through the nuclear shuttling of clathrin light chain 2 in plant cells.Science advances · 2025Article
- Article
- Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells.ACS omega · 2021Article
- Identification of Actin Filament-Associated Proteins in Giardia lamblia.Microbiology spectrum · 2021Article
- Measuring Endocytosis During Proliferative Cell Quiescence.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Wbox2: A clathrin terminal domain-derived peptide inhibitor of clathrin-mediated endocytosis.The Journal of cell biology · 2020Article
- A unique role for clathrin light chain A in cell spreading and migration.Journal of cell science · 2019Article
- Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma.International journal of molecular sciences · 2019Article
- Article
- HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.PLoS pathogens · 2017Article
- Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability.American journal of physiology. Cell physiology · 2017Article
- Clathrin in plant defense signaling and execution.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Endocytosis: Past, present, and future.Cold Spring Harbor perspectives in biology · 2014Article
- Endocytosis of viruses and bacteria.Cold Spring Harbor perspectives in biology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The roles of clathrin, its regulators, and the ESCRT (endosomal sorting complex required for transport) proteins are well defined in endocytosis. These proteins can also participate in intracellular pathways that are independent of endocytosis and even independent of the membrane trafficking function of these proteins. These nonendocytic functions involve unconventional biochemical interactions for some endocytic regulators, but can also exploit known interactions for nonendocytic functions. The molecular basis for the involvement of endocytic regulators in unconventional functions that influence the cytoskeleton, cell cycle, signaling, and gene regulation are described here. Through these additional functions, endocytic regulators participate in pathways that affect infection, glucose metabolism, development, and cellular transformation, expanding their significance in human health and disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.