ReviewCold Spring Harbor perspectives in biology2014
The neomuran revolution and phagotrophic origin of eukaryotes and cilia in the light of intracellular coevolution and a revised tree of life.
Review in Cold Spring Harbor perspectives in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 65 citations in OpenAlex.
- Quantifying the fitness contribution of phagocytosis.bioRxiv : the preprint server for biology · 2025Article
- The Structure of Cilium Inner Junctions Revealed by Electron Cryo-tomography.bioRxiv : the preprint server for biology · 2024Article
- Early Diversification of Membrane Intrinsic Proteins (MIPs) in Eukaryotes.Genome biology and evolution · 2024Article
- Phylogeny and Expansion of Serine/Threonine Kinases in Phagocytotic Bacteria in the Phylum Planctomycetota.Genome biology and evolution · 2024Article
- The role of mitochondrial energetics in the origin and diversification of eukaryotes.Nature ecology & evolution · 2022Article
- Review
- Phylogenetic analysis of mutational robustness based on codon usage supports that the standard genetic code does not prefer extreme environments.Scientific reports · 2021Article
- Origins of eukaryotic excitability.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- A central role of the endoplasmic reticulum in the cell emerges from its functional contact sites with multiple organelles.Cellular and molecular life sciences : CMLS · 2020Review
- Multidomain ribosomal protein trees and the planctobacterial origin of neomura (eukaryotes, archaebacteria).Protoplasma · 2020Review
- On the unity and diversity of cilia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Review
- A novel multidomain acyl-CoA carboxylase in Saccharopolyspora erythraea provides malonyl-CoA for de novo fatty acid biosynthesis.Scientific reports · 2019Article
- Multigene phylogeny and cell evolution of chromist infrakingdom Rhizaria: contrasting cell organisation of sister phyla Cercozoa and Retaria.Protoplasma · 2018Article
- Cell polarity: having and making sense of direction-on the evolutionary significance of the primary cilium/centrosome organ in Metazoa.Open biology · 2018Review
- Reply to Garg and Martin: The mechanism works.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Introgression of the Kinetoplast DNA: An Unusual Evolutionary Journey inCurrent genomics · 2018Review
- Vendozoa and selective forces on animal origin and early diversification: reply to Dufour and McIlroy (2017).Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Kingdom Chromista and its eight phyla: a new synthesis emphasising periplastid protein targeting, cytoskeletal and periplastid evolution, and ancient divergences.Protoplasma · 2018Article
- Symbiosis in eukaryotic evolution.Journal of theoretical biology · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three kinds of cells exist with increasingly complex membrane-protein targeting: Unibacteria (Archaebacteria, Posibacteria) with one cytoplasmic membrane (CM); Negibacteria with a two-membrane envelope (inner CM; outer membrane [OM]); eukaryotes with a plasma membrane and topologically distinct endomembranes and peroxisomes. I combine evidence from multigene trees, palaeontology, and cell biology to show that eukaryotes and archaebacteria are sisters, forming the clade neomura that evolved ~1.2 Gy ago from a posibacterium, whose DNA segregation and cell division were destabilized by murein wall loss and rescued by the evolving novel neomuran endoskeleton, histones, cytokinesis, and glycoproteins. Phagotrophy then induced coevolving serial major changes making eukaryote cells, culminating in two dissimilar cilia via a novel gliding-fishing-swimming scenario. I transfer Chloroflexi to Posibacteria, root the universal tree between them and Heliobacteria, and argue that Negibacteria are a clade whose OM, evolving in a green posibacterium, was never lost.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.