ArticleNucleic acids research2014
Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes.
Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42 citing papers in PubMed.
- Root-sourced 1-aminocyclopropane-1-carboxylic acid modulates development and adaptive responses to salinity in tomato.The Plant journal : for cell and molecular biology · 2026Article
- A novel CsbZIP26-CsSEP4-CsSPL18 regulatory module governs gynostemium morphology and floral architecture inHorticulture research · 2026Article
- Dynamic Transcriptome Profiling Reveals Key Regulatory Networks Underlying Curd Development in Cauliflower (International journal of molecular sciences · 2026Article
- Promoter Motif Profiling and Binding Site Distribution Analysis of Transcription Factors Predict Auto- and Cross-Regulatory Mechanisms inInternational journal of molecular sciences · 2025Article
- Integrated expression analysis to elucidate the role of miR394 during flowering in Arabidopsis thaliana.Plant cell reports · 2025Article
- TheHorticulture research · 2025Article
- The dynamic regulatory network of stamens and pistils in papaya.BMC plant biology · 2025Article
- Genome-Wide Investigation ofInternational journal of molecular sciences · 2025Article
- Single nucleotide polymorphisms in SEPALLATA 2 underlie fruit length variation in cucurbits.The Plant cell · 2024Article
- SEPALLATA-driven MADS transcription factor tetramerization is required for inner whorl floral organ development.The Plant cell · 2024Article
- 'Organ'ising Floral Organ Development.Plants (Basel, Switzerland) · 2024Review
- Reflections on the ABC model of flower development.The Plant cell · 2024Review
- Time-Course Transcriptomic Analysis Reveals Molecular Insights into the Inflorescence and Flower Development ofPlants (Basel, Switzerland) · 2024Article
- Expression Characterization of ABCDE Class MADS-Box Genes inPlants (Basel, Switzerland) · 2023Article
- Cracking the Floral Quartet Code: How Do Multimers of MIKCInternational journal of molecular sciences · 2023Review
- The Origin of Floral Quartet Formation-Ancient Exon Duplications Shaped the Evolution of MIKC-type MADS-domain Transcription Factor Interactions.Molecular biology and evolution · 2023Article
- Compressed variance component mixed model reveals epistasis associated with flowering inFrontiers in plant science · 2023Article
- Flower Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Exploiting plant transcriptomic databases: Resources, tools, and approaches.Plant communications · 2022Review
- An ortholog of the MADS-box gene SEPALLATA3 regulates stamen development in the woody plant Jatropha curcas.Planta · 2022Article
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3 authors.
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Abstract
The SEPALLATA (SEP) genes of Arabidopsis thaliana encode MADS-domain transcription factors that specify the identity of all floral organs. The four Arabidopsis SEP genes function in a largely yet not completely redundant manner. Here, we analysed interactions of the SEP proteins with DNA. All of the proteins were capable of forming tetrameric quartet-like complexes on DNA fragments carrying two sequence elements termed CArG-boxes. Distances between the CArG-boxes for strong cooperative DNA-binding were in the range of 4-6 helical turns. However, SEP1 also bound strongly to CArG-box pairs separated by smaller or larger distances, whereas SEP2 preferred large and SEP4 preferred small inter-site distances for binding. Cooperative binding of SEP3 was comparatively weak for most of the inter-site distances tested. All SEP proteins constituted floral quartet-like complexes together with the floral homeotic proteins APETALA3 (AP3) and PISTILLATA (PI) on the target genes AP3 and SEP3. Our results suggest an important part of an explanation for why the different SEP proteins have largely, but not completely redundant functions in determining floral organ identity: they may bind to largely overlapping, but not identical sets of target genes that differ in the arrangement and spacing of the CArG-boxes in their cis-regulatory regions.
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