Evidence map›Paper›PMID 25183456›Full record

ReviewHead and neck pathology2015

Sarcoidosis of the head and neck.

Arvind K Badhey, Sameep Kadakia, Ricardo L Carrau, Codrin Iacob, Azita Khorsandi

Open access · bronzeAbstract readReview
In one paragraph

Review in Head and neck pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Diagnosis and Management of Isolated Laryngeal Sarcoidosis: A Systematic Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. International journal of environmental research and public health · 2021
    Pooled it
  3. Mimickers of pituitary tumors.Neuro-oncology advances · 2025
    Article
  4. Beyond the Usual Suspects: Primary Premaxilla Sarcoidosis.Iranian journal of otorhinolaryngology · 2024
    Article
  5. Neurosarcoidosis - the Role of Magnetic Resonance Imaging in Diagnostics.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Phenotypes of Chronic Rhinosinusitis.The journal of allergy and clinical immunology. In practice · 2020
    Review
  10. Sarcoidosis of the paranasal sinuses.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Article
  11. Hybrid Imaging in Head and Neck Sarcoidosis.Journal of clinical medicine · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Arvind K BadheyAlbert Einstein College of Medicine, Bronx, NY, USA, arvind.badhey@med.einstein.yu.edu.
Sameep Kadakia
Ricardo L Carrau
Codrin Iacob
Azita Khorsandi
New York Eye and Ear Infirmary · USAlbert Einstein College of Medicine · USThe Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is a complex disorder that often times involves the head and neck. Despite the presence of strong clinical evidence, tissue diagnosis and imaging is needed for confirmation of the disease. Although typically managed medically, when found in the sinonasal tract or intracranially, it may necessitate the intervention of a rhinologist-skull base surgeon. This article seeks to provide a comprehensive review of head and neck sarcoidosis, as this fascinating disorder often poses a diagnostic and therapeutic challenge. A brief discussion of surgical treatment for pituitary lesions is also provided. Articles from 1997 to 2013 were selected and reviewed by three researchers utilizing the most recent literature regarding sarcoidosis in the head and neck. PubMed searches were conducted using search terms such as "sarcoidosis", "neurosarcoid", and "extra-pulmonary sarcoid", among many others. A large collection of articles was generated and reviewed by the team of authors, and appropriate information was extracted to compose a thorough and expansive review of the subject. 10-15 % of patients with sarcoidosis have head and neck manifestations. Sinonasal and pituitary sarcoidosis presents a diagnostic challenge owing to its non-specific symptoms. Although systemic steroid therapy is often the first time treatment, endoscopic surgery is commonly used to treat advanced pituitary sarcoidosis refractory to medical management. As tissue diagnosis and imaging is key, a multi-disciplinary team approach is advantageous. Our study collates the available literature on head and neck sarcoidosis to provide a comprehensive review of the subject. This provides helpful information to guide all practitioners involved in the care of these challenging patients, namely pathologists, radiologists, otolaryngologists, and skull base surgeons, in the workup and management of head and neck sarcoidosis.

Indexed as

Central Nervous System DiseasesParanasal Sinus DiseasesPituitary DiseasesSarcoidosisCombined Modality TherapyEndoscopyHumansPrevalenceSteroidsTreatment OutcomeSteroids

Identifiers

PMID25183456
PMCPMC4424214
OpenAlexW1991501990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.