ArticleAsian Pacific journal of tropical biomedicine2014
Anti-diabetic effects of Caulerpa lentillifera: stimulation of insulin secretion in pancreatic β-cells and enhancement of glucose uptake in adipocytes.
Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 81 citations in OpenAlex.
- Phytochemical analysis, antioxidant activity, and cytotoxic effects of Caulerpa lentillifera extracts inducing cell apoptosis and sub-G/G0-G1 cell cycle arrest in KON oral cancer cells.BMC complementary medicine and therapies · 2025Article
- In Vitro Studies of Pumpkin (Cucurbita moschata var. Kashi Harit) Seed Protein Fraction(s) to Evaluate Anticancer and Antidiabetic Properties.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- Ultrasonic-Assisted Extraction and Gastrointestinal Digestion Characteristics of Polysaccharides Extracted fromFoods (Basel, Switzerland) · 2024Article
- Chemical Constituents from the Roots ofPharmaceutics · 2023Article
- Ulvophyte Green AlgaeMolecules (Basel, Switzerland) · 2023Article
- Caulerpa lentillifera improves ethanol-induced liver injury and modulates the gut microbiota in rats.Current research in food science · 2023Article
- Hyaluronidase-inhibiting Polysaccharide fromJournal of applied glycoscience · 2023Article
- A Review on Nutrients, Phytochemicals, and Health Benefits of Green Seaweed,Foods (Basel, Switzerland) · 2022Review
- Novel Technologies for Seaweed Polysaccharides Extraction and Their Use in Food with Therapeutically Applications-A Review.Foods (Basel, Switzerland) · 2022Review
- Seasonal succession of bacterial communities in culturedOpen life sciences · 2022Article
- Amelioration of obesity-related metabolic disorders via supplementation ofFrontiers in nutrition · 2022Article
- The Enhancing Immune Response and Anti-Inflammatory Effects ofMolecules (Basel, Switzerland) · 2021Article
- Impact of A Cargo-Less Liposomal Formulation on Dietary Obesity-Related Metabolic Disorders in Mice.International journal of molecular sciences · 2020Article
- Stimulation of non-specific immunity, gene expression, and disease resistance in Nile Tilapia,Veterinary world · 2019Article
- Article
- MechanisticPharmacognosy magazine · 2018Article
- Article
- Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes.Journal of translational medicine · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate anti-diabetic effect of Caulerpa lentillifera (C. lentillifera).
methodsThe inhibitory effect of C. lentillifera extract on dipeptidyl peptidase-IV and α-glucosidase enzyme was measured in a cell free system. Then, interleukin-1β and interferon-γ induced cell death and insulin secretion were measured in rat insulinoma (RIN) cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and ELISA kit, respectively. Glucose uptake and glucose transporter expression were measured by fluorometry and western blotting, using 3T3-L1 adipocytes.
resultsC. lentillifera extract significantly decreased dipeptidyl peptidase-IV and α-glucosidase enzyme activities, and effectively inhibited cell death and iNOS expression in interleukin-1β and interferon-γ induced RIN cells. Furthermore, C. lentillifera extract significantly enhanced insulin secretion in RIN cells and glucose transporter expression and glucose uptake in 3T3-L1 adipocytes.
conclusionsThus, our results suggest that C. lentillifera could be used as a potential anti-diabetic agent.
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