SynthesisClinical orthopaedics and related research2015
Is sequestrectomy a viable alternative to microdiscectomy? A systematic review of the literature.
Synthesis in Clinical orthopaedics and related research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Surgical techniques and perioperative surgical outcomes after discectomy for calcified lumbar disc herniation: a review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Comparison of discectomy versus sequestrectomy in lumbar disc herniation: a meta-analysis of comparative studies.PloS one · 2015Pooled it
- Surgical treatment variations and intraoperative findings related to annular defects in a cohort of lumbar discectomy patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Comparison of recurrence and postoperative outcomes after endoscopic versus microsurgical sequestrectomy for lumbar disc herniation: 5-year experience.Journal of spine surgery (Hong Kong) · 2026Article
- Assessment of 'spin' in the abstracts of systematic reviews in leading orthopaedic surgery journals over the past 10 years: a cross-sectional methodological study.EFORT open reviews · 2026Article
- Article
- Role of surgery in primary lumbar disk herniation: WFNS spine committee recommendations.World neurosurgery: X · 2024Review
- Changes in Disc Height as a Prognostic Factor in Patients Undergoing Microscopic Discectomy.Journal of Korean Neurosurgical Society · 2024Article
- Treatment of L5-S1 Floating Calcified Lumbar Disc Herniation with Percutaneous Endoscopic Interlaminar Discectomy.Orthopaedic surgery · 2024Article
- Evaluation of Spin in Systematic Reviews and Meta-Analyses of Minimally Invasive Surgical Techniques and Standard Microdiscectomies for Treating Lumbar Disc Herniation.Global spine journal · 2024Review
- Review
- Surgical training in spine surgery: safety and patient-rated outcome.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- Article
- The modified transforaminal endoscopic technique in treating intracanalicular combining foraminal and/or extraforaminal lumbar disc herniations.Quantitative imaging in medicine and surgery · 2018Article
- Lumbar disc reherniation after transforaminal lumbar endoscopic discectomy.Annals of translational medicine · 2018Article
- Development of a bovine decellularized extracellular matrix-biomaterial for nucleus pulposus regeneration.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2016Article
- Effect of a New Annular Incision on Biomechanical Properties of the Intervertebral Disc.Orthopaedic surgery · 2016Article
- Recurrent lumbar disc herniation: Is there a correlation with the surgical technique? A multivariate analysis.Journal of craniovertebral junction & spineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraditionally, lumbar discectomy involves removal of the free disc fragment followed by aggressive or conservative excision of the intervertebral disc. In selected patients, however, it is possible to remove only the free fragment or sequester without clearing the intervertebral disc space. However, there is some controversy about whether that approach is sufficient to prevent recurrent symptoms and to provide adequate pain relief. QUESTIONS/PURPOSES: This systematic review was designed to pose two questions: (1) Does performing a sequestrectomy only without conventional microdiscectomy lead to an increased reherniation rate; and (2) is there a difference in the patient-reported levels of radicular pain?
methodsSystematic MEDLINE and EMBASE searches were carried out to identify all articles published in peer-reviewed journals reporting the outcomes of interest for conventional microdiscectomy versus sequestrectomy for lumbar disc herniation from L2 to the sacrum (Level III evidence and above); hand-searching of bibliographies was also performed. A minimum of Level II evidence was required with a followup rate of greater than 75%. Followup in all studies was from 18 to 86 months. Seven studies met the inclusion criteria for this review. The studies were analyzed for operating time, hospital stay, pre- and postoperative visual analog scale, and reherniation rate.
resultsPatients in both the microdiscectomy and sequestrectomy groups showed comparable improvement of visual analog scale (VAS) score for leg pain. VAS score improvement ranged from 5.6 to 6.5 points in the microdiscectomy groups and 5.5 to 6.6 in the sequestrectomy group. The reherniation rate in the microdiscectomy group ranged from 2.3% to 11.8% and in the sequestrectomy groups from 2% to 12.5%.
conclusionsThis review of the available literature suggests that, compared with conventional microdiscectomy, microsurgical lumbar sequestrectomy can achieve comparable reherniation rates and reduction in radicular pain when a small breach in the posterior fibrous ring is found intraoperatively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.