ArticleAsian Pacific journal of tropical biomedicine2014
Oral administration of leaf extracts of Momordica charantia affect reproductive hormones of adult female Wistar rats.
Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 39 citations in OpenAlex.
- A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals.Pharmaceutical biology · 2026Review
- In vitro cytotoxicity of medicinal plants used in prostate cancer management in Africa: a systematic review.Tropical medicine and health · 2026Review
- Promising roles ofJournal of agriculture and food research · 2023Article
- Natural products: potential treatments for cisplatin-induced nephrotoxicity.Acta pharmacologica Sinica · 2021Review
- Efficacy of Bottle Gourd Seeds' Extracts in Chemical Hazard Reduction Secreted as Toxigenic Fungi Metabolites.Toxins · 2021Article
- The Effect ofEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Recent Advances in Momordica charantia: Functional Components and Biological Activities.International journal of molecular sciences · 2017Review
- Bitter Melon Seed Extract does not Alter Photoperiodic Effects on Reproduction of Male Golden Hamsters.Development & reproduction · 2017Article
- Effect ofOncology letters · 2017Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the effect of graded doses of aqueous leaf extracts of Momordica charantia on fertility hormones of female albino rats.
methodsTWENTY ADULT, HEALTHY, FEMALE WISTAR RATS WERE DIVIDED INTO FOUR GROUPS: low dose (LD), moderate dose (MD) and high dose (HD) groups which received 12.5 g, 25.0 g, 50.0 g of the leaf extract respectively and control group that was given with water ad libatum.
resultEstrogen levels reduced by 6.40 nmol/L, 10.80 nmol/L and 28.00 nmol/L in the LD, MD and HD groups respectively while plasma progesterone of rats in the LD, MD and HD groups reduced by 24.20 nmol/L, 40.8 nmol/L and 59.20 nmol/L respectively.
conclusionOur study has shown that the antifertility effect of Momordica charantia is achieved in a dose dependent manner. Hence, cautious use of such medication should be advocated especially when managing couples for infertility.
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