ArticleAsian Pacific journal of tropical biomedicine2014
Antipyretic and antinociceptive activity of Diospyros lotus L. in animals.
Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 53 citations in OpenAlex.
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- Drying date plum (Diospyros lotus L.) fruit: Assessing rehydration properties, antioxidant activity, and phenolic compounds.Journal of food science · 2022Article
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- Antibacterial, Antifungal, Antioxidant, and Docking Studies of Potential Dinaphthodiospyrols fromACS omega · 2021Article
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- In vivo analgesic, anti-inflammatory, and sedative activity and a molecular docking study of dinaphthodiospyrol G isolated from Diospyros lotus.BMC complementary medicine and therapies · 2020Article
- Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.BMC complementary medicine and therapies · 2020Article
- Pharmacological evidence for the use ofBiochemistry and biophysics reports · 2020Article
- Analgesic and Anti-Inflammatory Activities of Diethyl Ether and n-Hexane Extract ofEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Phenolic Compounds and In Vitro Antibacterial and Antioxidant Activities of Three Tropic Fruits: Persimmon, Guava, and Sweetsop.BioMed research international · 2016Article
- Analgesic and Antipyretic Activities of Methanol Extract and Its Fraction from the Root of Schoenoplectus grossus.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects.Frontiers in pharmacology · 2015Article
- Antipyretic and antinociceptive potential of extract/fractions of Potentilla evestita and its isolated compound, acacetin.BMC complementary and alternative medicine · 2014Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate pharmacologically the traditional use of Diospyros lotus as antipyretic and antinociceptive in various animal models.
methodsIn vivo experimental models were used in this study. Antipyretic activity of extract/fractions was evaluated in brewer's yeast induced hyperthermic mice while antinociceptive activity was studied in acetic acid induced writhing test at 50 and 100 mg/kg i.p.
resultsThe crude extract strongly ameliorated the induced pyrexia during various assessment times. Upon fractionation, the antipyretic effects were strongly augmented by the chloroform and ethyl acetate fractions of the plant. However, hexane and butanol fractions were insignificant in their effect as antipyretic. The extract showed marked inhibition on the noxious simulation induced by post acetic acid injection. The effect was strongly supported by other fraction expect hexane.
conclusionsIn short, our study scientifically validated the traditional use of the plant as antipyretic.
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