Evidence map›Paper›PMID 25183111›Full record

ArticleAsian Pacific journal of tropical biomedicine2014

Protective effects of Moringa oleifera Lam. leaves against arsenic-induced toxicity in mice.

Afzal Sheikh, Fouzia Yeasmin, Smita Agarwal, Mashiur Rahman, Khairul Islam, Ekhtear Hossain, Shakhawoat Hossain, Md Rezaul Karim, Farjana Nikkon, Zahangir Alam Saud and 1 more

Abstract read
In one paragraph

Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biological properties ofF1000Research · 2024
    Pooled it
  2. Review
  3. Polyphenolics with Strong Antioxidant Activity fromMolecules (Basel, Switzerland) · 2022
    Article
  4. Protective effects of guarana (Food science & nutrition · 2021
    Article
  5. Protective Impacts ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  6. Comparative Analysis of Chemical Constituents ofMolecules (Basel, Switzerland) · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Afzal SheikhDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Fouzia YeasminDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Smita AgarwalDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Mashiur RahmanDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Khairul IslamDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Ekhtear HossainDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Shakhawoat HossainDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Md Rezaul KarimDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Farjana NikkonDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Zahangir Alam SaudDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.
Khaled HossainDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the protective role of leaves of Moringa oleifera (M. oleifera) Lam. against arsenic-induced toxicity in mice.

methodsSwiss albino male mice were divided into four groups. The first group was used as non-treated control group while, the second, third, and fourth groups were treated with M. oleifera leaves (50 mg/kg body weight per day), sodium arsenite (10 mg/kg body weight per day) and sodium arsenite plus M. oleifera leaves, respectively. Serum indices related to cardiac, liver and renal functions were analyzed to evaluate the protective effect of Moringa leaves on arsenic-induced effects in mice.

resultsIt revealed that food supplementation of M. oleifera leaves abrogated the arsenic-induced elevation of triglyceride, glucose, urea and the activities of alkaline phospatase, aspartate aminotransferase and alanine aminotransferase in serum. M. oleifera leaves also prevented the arsenic-induced perturbation of serum butyryl cholinesterase activity, total cholesterol and high density lipoprotein cholesterol.

conclusionsThe results indicate that the leaves of M. oleifera may be useful in reducing the effects of arsenic-induced toxicity.

Indexed as

Arsenic toxicityMoringa oleifera leavesSerum indices

Identifiers

PMID25183111
PMCPMC4025314

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.