ArticleAsian Pacific journal of tropical biomedicine2014
Anti-elastase, anti-tyrosinase and matrix metalloproteinase-1 inhibitory activity of earthworm extracts as potential new anti-aging agent.
Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 86 citations in OpenAlex.
- Glucosinolate- and Sulforaphane-Enriched Broccoli Extract as a Potential Dual-Action Antioxidant and Elastase Inhibitor.Foods (Basel, Switzerland) · 2026Article
- Integrated metabolite profiling and molecular docking reveal anti-aging potential of Clerodendrum infortunatum L. fractions.Scientific reports · 2026Article
- A Novel Bioactive Emulgel withGels (Basel, Switzerland) · 2026Article
- Synthesis and Biological Properties of Formulated Skin Serum Containing Coelomic Fluid of EarthwormRecent patents on biotechnology · 2026Article
- Bridging Phytochemistry and Cosmetic Science: Molecular Insights into the Cosmeceutical Promise ofInternational journal of molecular sciences · 2025Article
- Green Approach forAntioxidants (Basel, Switzerland) · 2025Article
- Phytoconstituent analysis, bioactivity, and safety evaluation of various colors of Chrysanthemum morifolium flower extracts for cosmetic application.Scientific reports · 2025Article
- Article
- Functional Properties and Components of Koenigia alpina Extract.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Pharmacological effects of bioactive agents in earthworm extract: A comprehensive review.Animal models and experimental medicine · 2024Review
- Bioprospection of the Antarctic DiatomsMarine drugs · 2024Article
- Cubeb (Frontiers in nutrition · 2024Article
- Effects of Water-Ethanol Extracts from FourPharmaceuticals (Basel, Switzerland) · 2023Article
- Choline chloride-based deep eutectic solvent as an inhibitor of metalloproteases (collagenase and elastase) in cosmetic formulation.3 Biotech · 2023Article
- Molecular Characterization ofInternational journal of molecular sciences · 2023Article
- Optimization and scale up of the enzymatic hydrolysis of Californian red worm protein (Heliyon · 2023Article
- Optimization of Cyclodextrin-Assisted Extraction of Phenolics fromMetabolites · 2023Article
- Biochemical Pilot Study on Effects of Pomegranate Seed Oil Extract and Cosmetic Cream on Neurologically Mediated Skin Inflammation in Animals and Humans: A Comparative Observational Study.Molecules (Basel, Switzerland) · 2023Observational
- Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction.Plants (Basel, Switzerland) · 2022Article
- Brewers' spent hop revalorization for the production of high added-value cosmetics ingredients with elastase inhibition capacity.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine whether earthworms of Eisenia fetida, Lumbricus rubellus and Eudrilus eugeniae extracts have elastase, tyrosinase and matrix metalloproteinase-1 (MMP-1) inhibitory activity.
methodsThe earthworms extract was screened for elastase, tyrosinase and MMP-1 inhibitory activity and compared with the positive controls. It was also evaluated for whitening and anti-wrinkle capacity.
resultsThe extract showed significantly (P<0.05) good elastase and tyrosinase inhibition and excellent MMP-1 inhibition compared to N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic acid.
conclusionsEarthworms extract showed effective inhibition of tyrosinase, elastase and MMP-1 activities. Therefore, this experiment further rationalizes the traditional use of this worm extracts which may be useful as an anti-wrinkle agent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.