ArticleThe Plant journal : for cell and molecular biology2014
Comparative expression profiling reveals gene functions in female meiosis and gametophyte development in Arabidopsis.
Article in The Plant journal : for cell and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Investigation of mechanisms underlying seedlessness in a Sangiovese somatic variant through comparative genomic and histological analyses.BMC plant biology · 2025Article
- Cytological analysis of flower development, insights into suitable growth area and genomic background: implications for Glehnia littoralis conservation and sustainable utilization.BMC plant biology · 2024Article
- Germline β-1,3-glucan deposits are required for female gametogenesis in Arabidopsis thaliana.Nature communications · 2024Article
- Signaling by the EPFL-ERECTA family coordinates female germline specification through the BZR1 family in Arabidopsis.The Plant cell · 2023Article
- Transcriptome Profiling Identifies Candidate Genes Contributing to Male and Female Gamete Development in SyntheticPlants (Basel, Switzerland) · 2022Article
- SDG2 regulates Arabidopsis inflorescence architecture through SWR1-ERECTA signaling pathway.iScience · 2021Article
- Characterization of germline development and identification of genes associated with germline specification in pineapple.Horticulture research · 2021Article
- High-throughput single-cell transcriptomics reveals the female germline differentiation trajectory in Arabidopsis thaliana.Communications biology · 2021Article
- Spatiotemporal control of miR398 biogenesis, via chromatin remodeling and kinase signaling, ensures proper ovule development.The Plant cell · 2021Article
- Apomixis and strategies to induce apomixis to preserve hybrid vigor for multiple generations.GM crops & food · 2021Review
- The Glycine-Rich Domain Protein GRDP2 Regulates Ovule Development via the Auxin Pathway inFrontiers in plant science · 2021Article
- Caught in the Act: Live-Cell Imaging of Plant Meiosis.Frontiers in plant science · 2021Review
- Gibberellin-mediated RGA-LIKE1 degradation regulates embryo sac development in Arabidopsis.Journal of experimental botany · 2020Article
- Floral transcriptomes reveal gene networks in pineapple floral growth and fruit development.Communications biology · 2020Article
- Article
- Comparative Expression Profiling Reveals Genes Involved in Megasporogenesis.Plant physiology · 2020Article
- Studies on genome size estimation, chromosome number, gametophyte development and plant morphology of salt-tolerant halophyte Suaeda salsa.BMC plant biology · 2019Article
- Identification of lncRNAs involved in rice ovule development and female gametophyte abortion by genome-wide screening and functional analysis.BMC genomics · 2019Article
- ArabidopsisPlant physiology · 2018Article
- Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Megasporogenesis is essential for female fertility, and requires the accomplishment of meiosis and the formation of functional megaspores. The inaccessibility and low abundance of female meiocytes make it particularly difficult to elucidate the molecular basis underlying megasporogenesis. We used high-throughput tag-sequencing analysis to identify genes expressed in female meiocytes (FMs) by comparing gene expression profiles from wild-type ovules undergoing megasporogenesis with those from the spl mutant ovules, which lack megasporogenesis. A total of 862 genes were identified as FMs, with levels that are consistently reduced in spl ovules in two biological replicates. Fluorescence-assisted cell sorting followed by RNA-seq analysis of DMC1:GFP-labeled female meiocytes confirmed that 90% of the FMs are indeed detected in the female meiocyte protoplast profiling. We performed reverse genetic analysis of 120 candidate genes and identified four FM genes with a function in female meiosis progression in Arabidopsis. We further revealed that KLU, a putative cytochrome P450 monooxygenase, is involved in chromosome pairing during female meiosis, most likely by affecting the normal expression pattern of DMC1 in ovules during female meiosis. Our studies provide valuable information for functional genomic analyses of plant germline development as well as insights into meiosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.