Evidence map›Paper›PMID 25182738›Full record

ReviewJournal of Alzheimer's disease : JAD2015

Eye movements in Alzheimer's disease.

Robert J Molitor, Philip C Ko, Brandon A Ally

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of Alzheimer's disease : JAD, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Ocular microtremor: a structured review.Experimental brain research · 2023
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Loss of neuronal population organization links pathology to behavior in a model of Alzheimer's disease.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. A novel eye-tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert J MolitorDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Philip C KoDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Brandon A AllyDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA Department of Psychology, Vanderbilt University, Nashville, TN, USA Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Cognitive and Neural Correlates of the Picture Superiority Effect in Alzheimer's.R01AG038471 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALLY, BRANDON A · 2011 to 2015
$1.6M
Using Pictures to Understand Recognition Memory in Alzheimer's DiseaseK23AG031925 · NIA · VANDERBILT UNIVERSITY · PI ALLY, BRANDON A · 2008 to 2012
$675k
NIA NIH HHS AG031925NIA NIH HHS AG038471NIA NIH HHS K23 AG031925NIA NIH HHS R01 AG038471
6 · The paper itself

Abstract

A growing body of literature has investigated changes in eye movements as a result of Alzheimer's disease (AD). When compared to healthy, age-matched controls, patients display a number of remarkable alterations to oculomotor function and viewing behavior. In this article, we review AD-related changes to fundamental eye movements, such as saccades and smooth pursuit motion, in addition to changes to eye movement patterns during more complex tasks like visual search and scene exploration. We discuss the cognitive mechanisms that underlie these changes and consider the clinical significance of eye movement behavior, with a focus on eye movements in mild cognitive impairment. We conclude with directions for future research.

Indexed as

Alzheimer DiseaseAttention Deficit Disorder with HyperactivityCognition DisordersEye MovementsHumansPhotic StimulationPsychomotor PerformanceAttentionmild cognitive impairmentsaccadesmooth pursuit

Identifiers

PMID25182738
PMCPMC5332166

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.