Evidence map›Paper›PMID 25182676›Full record

ReviewCurrent rheumatology reports2014

Mechanisms of post-traumatic osteoarthritis after ACL injury.

David Dare, Scott Rodeo

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05204836 (Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05204836 phase1terminatednot on this mapstarted 2023, after this paper: background citation

Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention

TypeinterventionalSponsorUniversity of CalgaryRan2023 to 2025Enrolled4ConditionsAnterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis KneeArmsZoledronic Acid Injection, Placebo
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Longitudinal analysis of tibiofemoral cartilage contact area and position in ACL reconstructed patients.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Neurophysiology of ACL Injury.Orthopedic reviews · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David DareHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA, dared@hss.edu.
Scott Rodeo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anterior cruciate ligament (ACL) rupture is a common and devastating injury with long-term sequelae that include meniscal tears, chondral injury, and an increased risk of knee osteoarthritis (OA). ACL reconstruction is recommended to protect against knee instability, reduce the likelihood of meniscal tears and further surgery, and enable earlier return to sporting activities. ACL reconstruction, however, does not reduce the incidence of early-onset OA. In this review, we discuss the factors before and after surgery that are believed to contribute to the premature development of degenerative joint disease.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionHumansKnee InjuriesOsteoarthritis, Knee

Identifiers

PMID25182676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.