Evidence map›Paper›PMID 25182280›Full record

ArticleAsian Pacific journal of tropical biomedicine2014

Hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of Candida albicans isolated from recurrent urinary tract infections.

Issam Alshami, Ahmed E Alharbi

Abstract read
In one paragraph

Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. UropathogenicAntibiotics (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Latin American Plants against Microorganisms.Plants (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Antibiofilm Activity ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Phytochemical Analysis, Antioxidant, Antimicrobial, and Anti-Swarming Properties ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  10. Review
  11. Article
  12. Antibacterial activity of Hibiscus rosa-sinensis L. red flower against antibiotic-resistant strains of Helicobacter pylori and identification of the flower constituents.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Indian journal of microbiology · 2020
    Article
  18. Article
  19. Review
  20. Natural therapeutics for urinary tract infections-a review.Future journal of pharmaceutical sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Issam AlshamiDepartment of Medical Microbiology and Immunology, College of Medicine, Taibah University, Almadinah, Saudi Arabia.
Ahmed E AlharbiDepartment of Medical Microbiology and Immunology, College of Medicine, Taibah University, Almadinah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the prevention of recurrent candiduria using natural based approaches and to study the antimicrobial effect of Hibiscus sabdariffa (H. sabdariffa) extract and the biofilm forming capacity of Candida albicans strains in the present of the H. sabdariffa extract.

methodsIn this particular study, six strains of fluconazole resistant Candida albicans isolated from recurrent candiduria were used. The susceptibility of fungal isolates, time-kill curves and biofilm forming capacity in the present of the H. sabdariffa extract were determined.

resultsVarious levels minimum inhibitory concentration of the extract were observed against all the isolates. Minimum inhibitory concentration values ranged from 0.5 to 2.0 mg/mL. Time-kill experiment demonstrated that the effect was fungistatic. The biofilm inhibition assay results showed that H. sabdariffa extract inhibited biofilm production of all the isolates.

conclusionsThe results of the study support the potential effect of H. sabdariffa extract for preventing recurrent candiduria and emphasize the significance of the plant extract approach as a potential antifungal agent.

Indexed as

BiofilmCandida albicansCandiduriaHibiscus sabdariffaUTIs

Identifiers

PMID25182280
PMCPMC3819477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.