Evidence map›Paper›PMID 25182228›Full record

GuidelineOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014

Clinician's Guide to Prevention and Treatment of Osteoporosis.

F Cosman, S J de Beur, M S LeBoff, E M Lewiecki, B Tanner, S Randall, R Lindsay, National Osteoporosis Foundation

Erratum issued 8 registry-linked trialsAbstract readGuideline
In one paragraph

Guideline in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 8 registered trials, which are not on this map. Cited by 1,515 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,515citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03036722 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effect of Phytoestrogen-rich Flaxseeds on Decreasing Bone Turnover in Postmenopausal Women Aged Between 50 -70 Years.

TypeinterventionalSponsorUniversity of ReadingRan2017 to 2018Enrolled44ConditionsBone Loss, Age Realted, Post MenopausalArmsFlaxseed, Placebo control porridge
NCT03293108 phase3unknown statusnot on this mapstarted 2017, after this paper: background citation

A Phase III, Randomized, Two-armed, Parallel, Double-blind, Active-controlled, Non-inferiority Clinical Trial to Determine the Non-inferior Therapeutic Efficacy and Safety Between Arylia (60 mg, Denosumab, Produced by AryoGen Pharmed) Compared With Prolia® (60 mg, Denosumab, the Reference Drug, Produced by Amgen Company) in the Improvement of Bone Mineral Densitometry (BMD) Among Osteoporotic Postmenopausal Women

TypeinterventionalSponsorAryoGen Pharmed Co.Ran2017 to 2020Enrolled190ConditionsOsteoporosisArmsDenosumab, calcium, vitamin D
NCT04229368 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications

TypeinterventionalSponsorBrigham and Women's HospitalRan2019 to 2024Enrolled900ConditionsHip Arthropathy, Knee Arthropathy, Vitamin D DeficiencyArmsVitamin D3
NCT04719650 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

The Pharmacokinetics and Pharmacodynamics Study of Intravenous Zoledronic Acid in Chinese Subjects With Low Bone Mass or Osteoporosis: a Randomized Placebo-controlled Trail

TypeinterventionalSponsorPeking University Third HospitalRan2021 to 2024Enrolled64ConditionsPostmenopausal OsteoporosisArmsZoledronic Acid Injection, Placebo
NCT05347082 nacompletednot on this mapstarted 2021, after this paper: background citation

Resolution of Hyperparathyroidism With High-dose Vitamin D Improves Osteoporosis in Multi-treated Postmenopausal Women

TypeinterventionalSponsorHospital Regional 1o de OctubreRan2021 to 2022Enrolled47ConditionsPostmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis DArmsCholecalciferol
NCT06502301 completednot on this mapstarted 2020, after this paper: background citation

Evaluation of Balance With Computerized Posturography Device and Clinical Tests in Patients With Postmenopausal Osteoporosis

TypeobservationalSponsorIstanbul University - CerrahpasaRan2020 to 2021Enrolled95ConditionsPostmenopausal Osteoporosis, Vertebral Fracture, Fracture of Vertebra, FallArmsCross-sectional study
NCT07419451 recruitingnot on this mapstarted 2025, after this paper: background citation

Health Literacy and Osteoporosis Awareness Levels Among Individuals in the Age Group at Risk for Osteoporosis: A Descriptive Cross-Sectional Study

Typeobservational_patient_registrySponsorBandırma Onyedi Eylül UniversityRan2025 to 2026Enrolled190ConditionsOsteoporosis, Health Literacy Level, Awareness and Knowledge LevelArmsPatients will only fill out a questionnaire.
NCT07486076 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

The effect of a health belief model-based education programme on osteoporosis awareness and health beliefs in woman at risk of osteoporosis: a randomised controlled trial

TypeinterventionalSponsorBartın UnıversityRan2026 to 2027Enrolled74ConditionsHealth Belief Model-Based Osteoporosis Education ProgrammeArmsOsteoporosis Education Based on the Health Belief Model
3 · Its place in the literature

Who cites it

1,515 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Exercise rehabilitation with tailored support for exercise adherence for people with vertebral fragility fractures is more effective than standard rehabilitation: the OPTIN randomised controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Trial
  11. Trial
  12. Article
  13. Article
  14. Differential efficacy of initial versus sequential combination of denosumab and teriparatide in osteoporosis at high fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  15. Real-world comparison of abaloparatide and romosozumab: effects on bone mineral density and three-dimensional hip structure.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  16. Article
  17. In vivo mechanical assessment of cortical bone rigidity enhances fracture discrimination beyond DXA in postmenopausal women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  18. Article
  19. Article
  20. Claims-based frailty index and risk of hospitalisation for hip fracture among adults aged 60-74 years in Tokyo, Japan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article

1,455 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

F CosmanHelen Hayes Hospital, West Haverstraw, NY, USA, cosmanf@helenhayeshosp.org.
S J de Beur
M S LeBoff
E M Lewiecki
B Tanner
S Randall
R Lindsay
National Osteoporosis Foundation

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Clinician's Guide to Prevention and Treatment of Osteoporosis was developed by an expert committee of the National Osteoporosis Foundation (NOF) in collaboration with a multispecialty council of medical experts in the field of bone health convened by NOF. Readers are urged to consult current prescribing information on any drug, device, or procedure discussed in this publication.

Indexed as

Absorptiometry, PhotonAgedBone DensityBone Density Conservation AgentsCalcium, DietaryDietFemaleHumansMaleMiddle AgedOsteoporosisOsteoporotic FracturesRisk AssessmentRisk FactorsSpinal FracturesVitamin DBone Density Conservation AgentsCalcium, DietaryVitamin D

Identifiers

PMID25182228
PMCPMC4176573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.