ArticleRadiation oncology (London, England)2014
Spinal bone metastases in gynecologic malignancies: a retrospective analysis of stability, prognostic factors and survival.
Article in Radiation oncology (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Trial
- Optimizing energy consumption in radiotherapy: standard vs. hypo-/ultra-hypofractionation and becoming SMART (specific, measurable, achievable in radiotherapy).Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Whole-body MRI: detecting bone metastases from prostate cancer.Japanese journal of radiology · 2022Review
- Comparative Analyses of Two Established Scores to Assess the Stability of Spinal Bone Metastases Before and After Palliative Radiotherapy.Frontiers in oncology · 2021Article
- The clinical utility of the Spinal Instability Neoplastic Score (SINS) system in spinal epidural metastases: a retrospective study.Spinal cord · 2020Article
- Article
- Stability and survival analysis of elderly patients with osteolytic spinal bone metastases after palliative radiotherapy : Results from a large multicenter cohort.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019Article
- Article
- Density of bone metastatic lesions increases after radiotherapy in patients with breast cancer.Journal of radiation research · 2019Article
- The influence of fractionated radiotherapy on the stability of spinal bone metastases: a retrospective analysis from 1047 cases.Radiation oncology (London, England) · 2018Article
- Survival and Stability of Patients with Urothelial Cancer and Spinal Bone Metastases after Palliative Radiotherapy.Radiology and oncology · 2018Article
- Spinal bone metastases in colorectal cancer: a retrospective analysis of stability, prognostic factors and survival after palliative radiotherapy.Radiation oncology (London, England) · 2017Article
- Prognostic factors for survival of women with unstable spinal bone metastases from breast cancer.Radiation oncology (London, England) · 2015Article
- Bone density as a marker for local response to radiotherapy of spinal bone metastases in women with breast cancer: a retrospective analysis.Radiation oncology (London, England) · 2015Article
- Changes in Spinal Instability After Conventional Radiotherapy for Painful Vertebral Bone Metastases.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this retrospective study was to evaluate the stability of spinal metastases in gynecologic cancer patients (pts) on the basis of a validated scoring system after radiotherapy (RT), to define prognostic factors for stability and to calculate survival.
methodsFourty-four women with gynecologic malignancies and spinal bone metastases were treated at our department between January 2000 and January 2012. Out of those 34 were assessed regarding stability using the Taneichi score before, 3 and 6 months after RT. Additionally prognostic factors for stability, overall survival, and bone survival (time between first day of RT of bone metastases and death from any cause) were calculated.
resultsBefore RT 47% of pts were unstable and 6 months after RT 85% of pts were stable. Karnofsky performance status (KPS) >70% (p = 0.037) and no chemotherapy (ChT) (p = 0.046) prior to RT were significantly predictive for response. 5-year overall survival was 69% and 1-year bone survival was 73%.
conclusionsRT is capable of improving stability of osteolytic spinal metastases from gynecologic cancer by facilitating re-ossification in survivors. KPS may be a predictor for response. Pts who received ChT prior to RT may require additional bone supportive treatment to overcome bone remodeling imbalance. Survival in women with bone metastases from gynecologic cancer remains poor.
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