ArticleActa cardiologica2014
Cardiac rehabilitation is associated with lasting improvements in cognitive function in older adults with heart failure.
Article in Acta cardiologica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Self-Care for the Prevention and Management of Cardiovascular Disease and Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association.Journal of the American Heart Association · 2017Guideline
- Decreases in body mass index after cardiac rehabilitation predict improved cognitive function in older adults with heart failure.Journal of the American Geriatrics Society · 2014Trial
- Exercise Training for Cerebrovascular and Cognitive Health in Adults at Risk of Cognitive Decline: A Scoping Review of Healthcare Translation and Evidence Gaps.Healthcare (Basel, Switzerland) · 2026Review
- Article
- Cardiovascular Prehabilitation in Patients Awaiting Heart Transplantation- Addressing Clinical Needs (the PREHAB HTx Study).CJC open · 2025Article
- Mapping research on cognitive impairment in heart failure patients: A bibliometric analysis from 2013 to 2022.Heliyon · 2024Review
- The Utility of High Intensity Interval Training to Improve Cognitive Aging in Heart Disease Patients.International journal of environmental research and public health · 2022Review
- Exercise and Cognitive Training Intervention Improves Self-Care, Quality of Life and Functional Capacity in Persons With Heart Failure.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Cardiorespiratory Fitness Mediates Cognitive Performance in Chronic Heart Failure Patients and Heart Transplant Recipients.International journal of environmental research and public health · 2020Article
- The Effectiveness of Exercise on Cognitive Performance in Individuals with Known Vascular Disease: A Systematic Review.Journal of clinical medicine · 2019Review
- Subcortical hyperintensities in the cholinergic system are associated with improvements in executive function in older adults with coronary artery disease undergoing cardiac rehabilitation.International journal of geriatric psychiatry · 2018Article
- Psychological Aspects of Heart Failure.Current cardiology reports · 2016Review
- Daily Physical Activity Is Associated with Subcortical Brain Volume and Cognition in Heart Failure.Journal of the International Neuropsychological Society : JINS · 2015Article
- Decreases in daily physical activity predict acute decline in attention and executive function in heart failure.Journal of cardiac failure · 2015Article
- Management of Heart Failure in Patients Nearing the End of Life-There is So Much More To Do.Cardiac failure review · 2015Article
- Reduced Gray Matter Volume Is Associated With Poorer Instrumental Activities of Daily Living Performance in Heart Failure.The Journal of cardiovascular nursingArticle
- Gender Differences in Cognitive Test Performance in Adults With Heart Failure.The Journal of cardiovascular nursingArticle
- COPD is associated with cognitive dysfunction and poor physical fitness in heart failure.Heart & lung : the journal of critical careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveHeart failure (HF) is a known risk factor for cognitive impairment. Cardiac rehabilitation (CR) may attenuate poor neurocognitive outcomes in HF via improved physical fitness--a significant promoter of cognitive function. However, no study has examined the possible acute and lasting benefits of CR on cognitive function in persons with HF. METHODS AND
resultsFifty-two patients with HF completed a 12-week Phase II CR program. All participants were administered neuropsychological testing and completed a brief physical fitness assessment at baseline, completion of CR (i.e. 12 weeks), and 12-month follow-up. Repeated measures analyses showed a significant time effect for both attention/executive function and memory (P < 0.05). Attention/executive function performance increased from baseline to 12 weeks and these gains remained up to 12 months; memory was unchanged from baseline to 12 weeks, but then improved between the 12-week and 12-month time points. Physical fitness improved from baseline to 12 weeks and these benefits were maintained 12 months later. Changes in physical fitness and cognitive function over time did not reach a statistically significant association, though poorer physical fitness was associated with decreased cognitive performance at the baseline and 12-month time points.
conclusionsCR is associated with both acute and lasting cognitive benefits in patients with HF. Prospective studies with extended follow-ups are needed to clarify the mechanisms that underpin cognitive improvements following CR (e.g., improved cerebral perfusion) and whether CR can ultimately reduce risk for cognitive decline and conditions like Alzheimer's disease in HF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.