Evidence map›Paper›PMID 25180981›Full record

ArticleNeuropsychology2015

Psychometric properties of the Penn Computerized Neurocognitive Battery.

Tyler M Moore, Steven P Reise, Raquel E Gur, Hakon Hakonarson, Ruben C Gur

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07699159 (Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions), which is not on this map. Cited by 220 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
220citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07699159 recruitingnot on this mapstarted 2025, after this paper: background citation

Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions (CALM): A Master Observational Trial

TypeobservationalSponsorCentre for Addiction and Mental HealthRan2025 to 2028Enrolled1,620ConditionsMultiple Mental Health Conditions, Child Mental Health, Youth Mental Health
3 · Its place in the literature

Who cites it

220 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mend the Gap: Online User-Led Adjuvant Treatment for Psychosis: A Systematic Review on Recent Findings.International journal of environmental research and public health · 2025
    Pooled it
  3. Trial
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  10. The Unique Roles of Executive Function in Co-Occurring Psychopathologies in Autism.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  11. Sex Differences in Psychopathology and Neurocognition in Community Youth With Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2026
    Article
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  13. Observational
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  17. Review
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160 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tyler M MooreBrain Behavior Laboratory, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Steven P ReiseDepartment of Psychology, University of California-Los Angeles.
Raquel E GurBrain Behavior Laboratory.
Hakon HakonarsonChildren's Hospital of Philadelphia.
Ruben C GurBrain Behavior Laboratory.

Funding

Neurodevelopmental Genomics: Trajectories of Complex PhenotypesRC2MH089983 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 2009 to 2011
$14.3M
2/2 Neurodevelopmental Genomics: Trajectories of Complex PhenotypesRC2MH089924 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI HAKONARSON, HAKON · 2009 to 2011
$10.7M
SCHIZOPHRENIA: A NEUROPSYCHIATRIC PERSPECTIVET32MH019112 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 1990 to 2024
$6.2M
NIMH NIH HHS MH019112NIMH NIH HHS MH089924NIMH NIH HHS MH089983NIMH NIH HHS RC2 MH089924NIMH NIH HHS RC2 MH089983NIMH NIH HHS T32 MH019112
6 · The paper itself

Abstract

objectiveThe Penn Computerized Neurocognitive Battery (CNB) was designed to measure performance accuracy and speed on specific neurobehavioral domains using tests that were previously validated with functional neuroimaging. The goal of the present study was to evaluate the neuropsychological theory used to construct the CNB by confirming the factor structure of the tests composing it.

methodIn a large community sample (N = 9,138; age range 8-21), we performed a correlated-traits confirmatory factor analysis (CFA) and multiple exploratory factor analyses (EFAs) on the 12 CNB measures of Efficiency (which combine Accuracy and Speed). We then performed EFAs of the Accuracy and Speed measures separately. Finally, we performed a confirmatory bifactor analysis of the Efficiency scores. All analyses were performed with Mplus using maximum likelihood estimation.

resultsRESULTS strongly support the a priori theory used to construct the CNB, showing that tests designed to measure executive, episodic memory, complex cognition, and social cognition aggregate their loadings within these domains. When Accuracy and Speed were analyzed separately, Accuracy produced 3 reliable factors: executive and complex cognition, episodic memory, and social cognition, while speed produced 2 factors: tests that require fast responses and those where each item requires deliberation. The statistical "Fit" of almost all models described above was acceptable (usually excellent).

conclusionsBased on the analysis from these large-scale data, the CNB offers an effective means for measuring the integrity of intended neurocognitive domains in about 1 hour of testing and is thus suitable for large-scale clinical and genomic studies.

Indexed as

Memory, EpisodicNeuropsychological TestsAdolescentChildCognitionCognition DisordersFemaleHumansMalePsychometricsReaction TimeYoung Adult

Identifiers

PMID25180981
PMCPMC4345134

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.