ArticleTranslational psychiatry2014
The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.
Article in Translational psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Multivariate genetic analyses test for the presence of a general 'JCPP advances · 2026Article
- Identifying Neurodevelopmental Domain Subgroups in Autism and ADHD.Journal of autism and developmental disorders · 2026Article
- Diversity of words and words for diversity.Frontiers in psychiatry · 2026Article
- Autism and ADHD traits, effortful control and mental health during the transition from elementary to junior high schools.Scientific reports · 2025Article
- Effects of Bilingualism on Executive Function of Children with Neurodevelopmental Disorders: A Scoping Review.Children (Basel, Switzerland) · 2025Review
- Neuropsychiatric symptoms in siblings of children with Tourette syndrome in the EMTICS study.JCPP advances · 2025Article
- Sex-Differential Trajectories of Domain-Specific Associations Between Autistic Traits and Co-Occurring Emotional-Behavioral Concerns in Autistic Children.Autism research : official journal of the International Society for Autism Research · 2025Article
- Associations between ADHD and risk of six psychiatric disorders: a Mendelian randomization study.BMC psychiatry · 2024Article
- Attention-deficit/hyperactivity disorder symptoms and subsequent cardiometabolic disorders in adults: investigating underlying mechanisms using a longitudinal twin study.BMC medicine · 2023Article
- Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes.Neuroscience and biobehavioral reviews · 2023Review
- Probing the overarching continuum theory: data-driven phenotypic clustering of children with ASD or ADHD.European child & adolescent psychiatry · 2023Article
- Annual Research Review: Perspectives on progress in ADHD science - from characterization to cause.Journal of child psychology and psychiatry, and allied disciplines · 2023Review
- Common genetic risk factors in ASD and ADHD co-occurring families.Human genetics · 2023Article
- Diagnostic assessment of autism in adults - current considerations in neurodevelopmentally informed professional learning with reference to ADOS-2.Frontiers in psychiatry · 2023Article
- Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder: Shared or Unique Neurocognitive Profiles?Research on child and adolescent psychopathology · 2023Article
- Bibliometric Analysis of Research Themes and Trends of the Co-Occurrence of Autism and ADHD.Neuropsychiatric disease and treatment · 2023Review
- The time is ripe for the renaissance of autism treatments: evidence from clinical practitioners.Frontiers in integrative neuroscience · 2023Article
- Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.Nature genetics · 2022Article
- ASD symptoms in adults with ADHD: a preliminary study using the ADOS-2.European archives of psychiatry and clinical neuroscience · 2022Article
- Autism Spectrum Disorder and Mental Health Problems: Patterns of Difficulties and Longitudinal Trajectories in a Population-Based Twin Sample.Journal of autism and developmental disorders · 2022Article
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Authors and funding
4 authors.
Funding
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Abstract
Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17,770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r(p) 0.33 to 0.40). ASDsc also correlated moderately with IA (females r(p) 0.29 and males r(p) 0.35) but only modestly with HI (females r(p) 0.17 and males r(p) 0.20). Genetic correlations ranged from 0.22 to 0.64 and were strongest between ASDr and IA and HI. Sex differences were virtually absent. The ASDr dimension (reflecting restricted, repetitive and stereotyped patterns of behavior, interests and activities) showed the strongest association with dimensions of ADHD, on a phenotypic, genetic and environmental level. This study opens new avenues for molecular genetic research. As our findings demonstrated that genetic overlap between disorders is dimension-specific, future gene-finding studies on psychiatric comorbidity should focus on carefully selected genetically related dimensions of disorders.
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