SynthesisSchizophrenia bulletin2015
The Epidemiology and Associated Phenomenology of Formal Thought Disorder: A Systematic Review.
Synthesis in Schizophrenia bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between formal thought disorders, neurocognition and functioning in the early stages of psychosis: a systematic review of the last half-century studies.European archives of psychiatry and clinical neuroscience · 2022Pooled it
- The link between formal thought disorder and social functioning in schizophrenia: A meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2020Pooled it
- Psychosocial Interventions, Recovery, and Mediating Mechanisms in Schizophrenia-Spectrum Disorders: A Systematic Review and Meta-Analysis of Longitudinal Studies.Brain sciences · 2026Review
- Cross-linguistic benchmarking of NLP metrics for psychosis research.NPJ digital medicine · 2026Article
- Reading between the lines: Combining pause dynamics and semantic coherence for automated assessment of thought disorder.Neuropsychologia · 2026Article
- "A room of one's own": Exploring the role of delusions and social isolation on disorganisation in thought disorder.Social psychiatry and psychiatric epidemiology · 2026Article
- Increasing participation of people with thought disorder in clinical research.European psychiatry : the journal of the Association of European Psychiatrists · 2026Review
- Linking speech patterns to brain structure in affective and psychotic disorders: an integrative natural language processing approach.Molecular psychiatry · 2026Article
- Rethinking language, cognition and assessment in psychosis: How bilingualism challenges psychiatry and how natural language processing can help.Schizophrenia (Heidelberg, Germany) · 2026Review
- A Unified Attention-Based Account of Semantic Impairment in Schizophrenia.Schizophrenia bulletin · 2026Article
- Exploring the interplay between language use and cognitive function in schizophrenia spectrum disorders: Insights from patients, first degree relatives, and healthy controls.Schizophrenia research. Cognition · 2026Review
- Clinical psychopathology-based early relapse prediction model using speech and language in psychosis.Schizophrenia research. Cognition · 2026Review
- Diagnostic Utility of Formal Thought Disorder Between Affective and Non-Affective Psychosis: A Machine Learning Approach.The Psychiatric quarterly · 2026Article
- Linking spontaneous speech, cognition, and psychopathology across affective and psychotic disorders: A network approach.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Relationship between cognitive reserve (education), social cognition and negative symptoms.Schizophrenia research. Cognition · 2025Article
- Formal Thought Disorder in Schizophrenia: A Problematic History.Schizophrenia bulletin · 2025Review
- Transdiagnostic types of formal thought disorder and their association with gray matter brain structure: a model-based cluster analytic approach.Molecular psychiatry · 2025Article
- Binomial order is a speech marker of psychosis and thought disorder.Scientific reports · 2025Article
- Differential structural cortical correlates of positive, negative, and linguistic control formal thought disorder dimensions in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Correlation Analysis of Acute Psychotic Symptom Domain Severity and Fractional Anisotropy of Brain White Matter Tracts in Schizophrenia.Sovremennye tekhnologii v meditsine · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAuthors of the Diagnostic and Statistical Manual, Fifth Edition (DSM-V) have recommended to "integrate dimensions into clinical practice." The epidemiology and associated phenomenology of formal thought disorder (FTD) have been described but not reviewed. We aimed to carry out a systematic review of FTD to this end.
methodsA systematic review of FTD literature, from 1978 to 2013, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
resultsA total of 881 abstracts were reviewed and 120 articles met inclusion criteria; articles describing FTD factor structure (n = 15), prevalence and longitudinal course (n = 41), role in diagnosis (n = 22), associated clinical variables (n = 56), and influence on outcome (n = 35) were included. Prevalence estimates for FTD in psychosis range from 5% to 91%. Dividing FTD into domains, by factor analysis, can accurately identify 91% of psychotic diagnoses. FTD is associated with increased clinical severity. Poorer outcomes are predicted by negative thought disorder, more so than the typical construct of "disorganized speech."
conclusionFTD is a common symptom of psychosis and may be considered a marker of illness severity. Detailed dimensional assessment of FTD can clarify diagnosis and may help predict prognosis.
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