Evidence map›Paper›PMID 25180263›Full record

ReviewPhysiology (Bethesda, Md.)2014

Dynamic multiphoton microscopy: focusing light on acute kidney injury.

Andrew M Hall, Bruce A Molitoris

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Advances in Renal Cell Imaging.Seminars in nephrology · 2018
    Review
  13. Deep insights: intravital imaging with two-photon microscopy.Pflugers Archiv : European journal of physiology · 2016
    Review
  14. Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury.International journal of molecular sciences · 2016
    Review
  15. Intravital imaging in the kidney.Current opinion in nephrology and hypertension · 2016
    Review
  16. Review
  17. In vivo microscopy.Nephrologie & therapeutique · 2016
    Review
  18. Renal Hemodynamics in AKI: In Search of New Treatment Targets.Journal of the American Society of Nephrology : JASN · 2016
    Article
  19. Article
  20. Nephrology research--the past, present and future.Nature reviews. Nephrology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew M HallInstitute of Anatomy, University of Zurich, Zurich, Switzerland; and andrew.hall@uzh.ch.
Bruce A MolitorisIndiana University School of Medicine, Indiana Center for Biological Microscopy, Indianapolis, Indiana.

Funding

PROBE DELIVERY COREP30DK079312 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MOLITORIS, BRUCE A · 2007 to 2021
$17.1M
Proximal Tubule Albumin Transport in Disease States.R01DK091623 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOLITORIS, BRUCE A · 2011 to 2021
$4.3M
Utilizing siRNA to Minimize Nephrotoxic InjuryR01DK088934 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ATKINSON, SIMON J., MOLITORIS, BRUCE A · 2011 to 2014
$1.4M
NIDDK NIH HHS DK-079312NIDDK NIH HHS DK-088934NIDDK NIH HHS DK-091623NIDDK NIH HHS P30 DK079312NIDDK NIH HHS R01 DK088934NIDDK NIH HHS R01 DK091623
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a major global health problem; much research has been conducted on AKI, and numerous agents have shown benefit in animal studies, but none have translated into treatments. There is, therefore, a pressing unmet need to increase knowledge of the pathophysiology of AKI. Multiphoton microscopy (MPM) provides a tool to non-invasively visualize dynamic events in real time and at high resolution in rodent kidneys, and in this article we review its application to study novel mechanisms and treatments in different forms of AKI.

Indexed as

Diagnostic ImagingMicroscopy, Fluorescence, MultiphotonAcute Kidney InjuryAnimalsDisease Models, AnimalHumansKidneySepsis

Identifiers

PMID25180263
PMCPMC4214830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.