ArticleAIDS research and treatment2014
Serum Micronutrient Status of Haart-Naïve, HIV Infected Children in South Western Nigeria: A Case Controlled Study.
Article in AIDS research and treatment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Growing Up with HIV: A Comprehensive Review of Treatment and Care in Low- and Middle-Income Countries.Current HIV/AIDS reports · 2025Review
- Review
- Micronutrients and nutritional status among children living with HIV with and without severe acute malnutrition: IMPAACT P1092.BMC nutrition · 2023Article
- Article
- Role of Selenium in Viral Infections with a Major Focus on SARS-CoV-2.International journal of molecular sciences · 2021Review
- Nutrition in HIV-Infected Infants and Children: Current Knowledge, Existing Challenges, and New Dietary Management Opportunities.Advances in nutrition (Bethesda, Md.) · 2021Review
- Micronutrient levels and their effects on the prognosis of visceral leishmaniasis treatment, a prospective cohort study.BMC infectious diseases · 2020Article
- The inhibition of H1N1 influenza induced apoptosis by sodium selenite through ROS-mediated signaling pathways.RSC advances · 2020Article
- Selenium, Selenoproteins and Viral Infection.Nutrients · 2019Review
- Selenium, Selenoproteins, and Immunity.Nutrients · 2018Review
- Zinc, copper, CD4 T-cell count and some hematological parameters of HIV-infected subjects in Southern Nigeria.Integrative medicine research · 2018Article
- Elements of kitchen toxicology to exploit the value of traditional (African) recipes: The case ofToxicology reports · 2017Article
- Magnitude of cytopenias among HIV-infected children in Bahir Dar, northwest Ethiopia: a comparison of HAART-naïve and HAART-experienced children.HIV/AIDS (Auckland, N.Z.) · 2017Article
- Association between Zinc Status and Human Immunodeficiency Virus Severity in Infected Nigerian Children at Ogbomoso, Nigeria.International journal of applied & basic medical researchArticle
- Serum Zinc Levels in Apparently Healthy Children in Nigeria: Are They Acceptable.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Though micronutrients are vital in the pathogenesis of human immunodeficiency virus infection, most studies have been conducted in adults. Knowledge of the status of key micronutrients in HIV infected African children will indicate if supplementation may be beneficial to these children living in this resource-poor region. Objectives. We sought to determine the micronutrient status and associated factors of HAART-naïve HIV infected children and compare them with those of the HIV negative controls. Methods. We enrolled 70 apparently stable HAART naïve HIV infected children. Seventy age and sex matched HIV negative children were equally enrolled as the controls. Their social class, anthropometry, clinical stage, CD4 counts, serum zinc, selenium, and vitamin C were determined. Results. The prevalence of zinc, selenium, and vitamin C deficiency in HIV infected subjects was 77.1%, 71.4%, and 70.0%, respectively, as compared to 44.3%, 18.6%, and 15.7% in HIV negative controls. Among the HIV infected subjects, 58.6% were deficient in the three micronutrients. Micronutrient status was related to the weight, clinical, and immunological stages but not BMI or social class. Conclusion. Deficiency of these key micronutrients is widely prevalent in HAART naïve HIV infected children irrespective of social class. This suggests that supplementation trial studies may be indicated in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.