Observational studyAnatolian journal of cardiology2015
The role of isovolumic acceleration in predicting subclinical right and left ventricular systolic dysfunction in patient with metabolic syndrome.
Observational study in Anatolian journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Improvements of right ventricular function after intervention with CPAP in patients with obstructive sleep apnoea.Echo research and practice · 2024Article
- Subclinical Left Ventricular Dysfunction in Children and Adolescence With Thalassemia Intermedia.Frontiers in pediatrics · 2022Article
- Tissue Doppler imaging is a sensitive echocardiographic technique to detect subclinical systolic and diastolic dysfunction of both ventricles in type 1 diabetes mellitus.BMC cardiovascular disorders · 2016Article
- Early detection of ventricular dysfunction in LADA using novel tissue Doppler parameters: A case-control study.Diabetes & vascular disease researchObservational
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to assess subclinical left (LV) and right ventricular (RV) dysfunction novel load-independent isovolumic myocardial acceleration (IVA) derived from tissue Doppler imaging (TDI) in patient with metabolic syndrome (MetS).
methodsThis study had an observational case-control design. The study included 133 subjects which were divided into two groups: 75 patients with MetS and 58 controls without MetS. MetS was defined by the presence of ≥3 criteria according to ATP-NCEP III guidelines. All the subjects underwent laboratory blood tests and complete conventional echocardiography and TDI. Student's t, Mann-Whitney U, Pearson's, and multiple regression analysis were used for statistical analysis.
resultsThere were no significant difference between two groups in terms of traditional echocardiographic parameters. The diastolic and global functions of both ventricles were significantly impaired in MetS group. The TDI-derived IVA of the LV and the RV was significantly lower in patients with MetS (3.2±0.9 vs. 4.0±1.4, p<0.001 and 2.6±0.7 vs. 3.1±0.9, p=0.001, respectively). Whereas, TDI derived systolic velocity (Sa), and peak myocardial velocity during isovolumic contraction (IVV) of both ventricles were similar between the two groups. In the multiple regression analysis, waist circumference and diastolic blood pressure were found to be an independent determinant of IVA of LV (b=-.223, 95% CI=-.034 -.002, p=0.004) and RV (b=-.527, 95% CI=-.085 -.020, p=0.002) respectively.
conclusionMetS affects global, diastolic, and systolic functions of two ventricles. This disruption lead to decreased function of heart was related with raised risk factors of MetS.
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