ReviewMatrix biology : journal of the International Society for Matrix Biology2014
Resident mesenchymal progenitors of articular cartilage.
Review in Matrix biology : journal of the International Society for Matrix Biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Co-delivery of IL-1Ra and SOX9 via AAV inhibits inflammation and promotes cartilage repair in surgically induced osteoarthritis animal models.Gene therapy · 2025Article
- YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis.Journal of orthopaedic translation · 2024Article
- Suramin enhances chondrogenic properties by regulating the p67Bone & joint research · 2022Article
- Meniscus Regeneration With Multipotent Stromal Cell Therapies.Frontiers in bioengineering and biotechnology · 2022Review
- Candidates for Intra-Articular Administration Therapeutics and Therapies of Osteoarthritis.International journal of molecular sciences · 2021Review
- Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration.Cell research · 2021Article
- Elder Mice Exhibit More Severe Degeneration and Milder Regeneration in Temporomandibular Joints Subjected to Bilateral Anterior Crossbite.Frontiers in physiology · 2021Article
- Biosafety evaluation of culture-expanded human chondrocytes with growth factor cocktail: a preclinical study.Scientific reports · 2020Article
- LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage.Scientific reports · 2020Article
- Implementation of Endogenous and Exogenous Mesenchymal Progenitor Cells for Skeletal Tissue Regeneration and Repair.Bioengineering (Basel, Switzerland) · 2020Review
- Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA.Stem cell research & therapy · 2020Article
- Neural EGFL like 1 as a potential pro-chondrogenic, anti-inflammatory dual-functional disease-modifying osteoarthritis drug.Biomaterials · 2020Article
- RSK-3 promotes cartilage regeneration via interacting with rpS6 in cartilage stem/progenitor cells.Theranostics · 2020Article
- Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Article
- Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.PLoS biology · 2019Article
- The Link Between Inflammaging and Degenerative Joint Diseases.International journal of molecular sciences · 2019Review
- Concise Review: Stem/Progenitor Cell Proteoglycans Decorated with 7-D-4, 4-C-3, and 3-B-3(-) Chondroitin Sulfate Motifs Are Morphogenetic Markers of Tissue Development.Stem cells (Dayton, Ohio) · 2018Review
- Review
- Profiling of Stem/Progenitor Cell Regulatory Genes of the Synovial Joint by Genome-Wide RNA-Seq Analysis.BioMed research international · 2018Article
- [Research progress of intervertebral disc endogenous stem cells for intervertebral disc regeneration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Articular cartilage has poor capacity of self-renewal and repair. Insufficient number and activity of resident mesenchymal (connective tissue) progenitors is likely one of the underlying reasons. Chondroprogenitors reside not only in the superficial zone of articular cartilage but also in other zones of articular cartilage and in the neighboring tissues, including perichondrium (groove of Ranvier), synovium and fat pad. These cells may respond to injury and contribute to articular cartilage healing. In addition, marrow stromal cells can migrate through subchondral bone when articular cartilage is damaged. We should develop drugs and methods that correctly stimulate resident progenitors for improvement of repair and inhibition of degenerative changes in articular cartilage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.