Evidence map›Paper›PMID 25179069›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2014

Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data.

Nafeesa N Dhalwani, Lisa Szatkowski, Tim Coleman, Linda Fiaschi, Laila J Tata

Abstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Development of "Baby, Me, & NRT": A Behavioral Intervention to Improve the Effectiveness of Nicotine Replacement Therapy in Pregnancy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  9. Development and Content Validation of a Questionnaire for Measuring Beliefs About Using Nicotine Replacement Therapy for Smoking Cessation in Pregnancy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Interest in and Use of Smoking Cessation Support Across Pregnancy and Postpartum.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  15. Article
  16. Article
  17. Stillbirth Among Women Prescribed Nicotine Replacement Therapy in Pregnancy: Analysis of a Large UK Pregnancy Cohort.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nafeesa N DhalwaniDivision of Primary Care, and doctoral student, Division of Epidemiology and Public Health, University Of Nottingham, Nottingham, UK.
Lisa SzatkowskiDivision of Epidemiology and Public Health, University Of Nottingham, Nottingham, UK.
Tim ColemanDivision of Primary Care, University Of Nottingham, Nottingham, UK.
Linda FiaschiDivision of Epidemiology and Public Health, University Of Nottingham, Nottingham, UK.
Laila J TataDivision of Epidemiology and Public Health, University Of Nottingham, Nottingham, UK.

Funding

Department of Health RP-PG-0109-10020Medical Research Council MR/K023195/1
6 · The paper itself

Abstract

backgroundLicensing arrangements for nicotine replacement therapy (NRT) in the UK were broadened in 2005 to allow prescribing to pregnant smokers. However, estimates of NRT prescribing in pregnant females in the UK are currently lacking.

aimTo assess trends in NRT prescribing around pregnancy, and variation in prescribing by maternal characteristics. DESIGN AND

settingPopulation-based descriptive study using pregnancy data from The Health Improvement Network primary care database, 2001-2012.

methodNRT prescriptions were identified during pregnancy and in the 9 months before and after. Annual prescribing prevalence was calculated. Logistic regression was used to assess females' likelihood of receiving prescriptions by maternal characteristics.

resultsOf 388 142 pregnancies studied, NRT was prescribed in 7551 for an average duration of 2 weeks. The prescribing prevalence of NRT increased from 0.03% (0.7% in smokers) in 2001 to 2.6% (11.4% in smokers) in 2005, after which it remained stable. Prescribing prevalence of NRT before and after pregnancy was half the prevalence during pregnancy. The odds of prescribing NRT during pregnancy in smokers increased with socioeconomic deprivation (OR = 1.29, 95% CI = 1.15 to 1.45 in the most compared with the least deprived group). Prescribing was 33% higher in pregnant smokers with asthma (OR = 1.33, 95% CI = 1.22 to 1.45) and mental illness (OR = 1.33, 95% CI = 1.23 to 1.44) compared with smokers without these diagnoses.

conclusionNRT prescribing is higher during pregnancy compared with before and after, and is higher in smokers from more socioeconomically deprived groups, those with asthma or those diagnosed mental illness.

Indexed as

Primary Health CareAdultAttitude of Health PersonnelDirective CounselingFemaleHumansNicotinic AgonistsPractice Patterns, Physicians'PregnancyPregnancy ComplicationsResearch DesignSmokingSmoking CessationTobacco Use Cessation DevicesUnited KingdomNicotinic Agonistsnicotine replacement therapypregnancyprescribingsmoking cessation

Identifiers

PMID25179069
PMCPMC4141612

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.