Evidence map›Paper›PMID 25179068›Full record

Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2014

Structural abnormalities and persistent complaints after an ankle sprain are not associated: an observational case control study in primary care.

John M van Ochten, Marinka C E Mos, Nienke van Putte-Katier, Edwin H G Oei, Patrick J E Bindels, Sita M A Bierma-Zeinstra, Marienke van Middelkoop

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. [Correlation analysis of anterior tibiotalar fat pad classification and anterior talofibular ligament injury based on MRI].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
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  10. Decreased perceived ankle and knee joint health in individuals with perceived chronic ankle instability.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John M van OchtenDepartment of Radiology, Albert Schweitzer Hospital Dordrecht, the Netherlands.
Marinka C E MosDepartment of Radiology, Albert Schweitzer Hospital Dordrecht, the Netherlands.
Nienke van Putte-KatierDepartment of Radiology, Albert Schweitzer Hospital Dordrecht, the Netherlands.
Edwin H G OeiDepartment of Radiology, Erasmus MC Medical University Rotterdam, the Netherlands.
Patrick J E BindelsDepartment of Radiology, Erasmus MC Medical University Rotterdam, the Netherlands.
Sita M A Bierma-ZeinstraDepartment of Radiology, Erasmus MC Medical University Rotterdam, the Netherlands.
Marienke van MiddelkoopDepartment of General Practice, Erasmus MC Medical University Rotterdam, the Netherlands.
Albert Schweitzer Ziekenhuis · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersistent complaints are very common after a lateral ankle sprain.

aimTo investigate possible associations between structural abnormalities on radiography and MRI, and persistent complaints after a lateral ankle sprain. DESIGN AND

settingObservational case control study on primary care patients in general practice.

methodPatients were selected who had visited their GP with an ankle sprain 6-12 months before the study; all received a standardised questionnaire, underwent a physical examination, and radiography and MRI of the ankle. Patients with and without persistent complaints were compared regarding structural abnormalities found on radiography and MRI; analyses were adjusted for age, sex, and body mass index.

resultsOf the 206 included patients, 98 had persistent complaints and 108 did not. No significant differences were found in structural abnormalities between patients with and without persistent complaints. In both groups, however, many structural abnormalities were found on radiography in the talocrural joint (47.2% osteophytes and 45.1% osteoarthritis) and the talonavicular joint (36.5% sclerosis). On MRI, a high prevalence was found of bone oedema (33.8%) and osteophytes (39.5) in the talocrural joint; osteophytes (54.4%), sclerosis (47.2%), and osteoarthritis (55.4%, Kellgren and Lawrence grade >1) in the talonavicular joint, as well as ligament damage (16.4%) in the anterior talofibular ligament.

conclusionThe prevalence of structural abnormalities is high on radiography and MRI in patients presenting in general practice with a previous ankle sprain. There is no difference in structural abnormalities, however, between patients with and without persistent complaints. Using imaging only will not lead to diagnosis of the explicit reason for the persistent complaint.

Indexed as

Magnetic Resonance ImagingTomography, X-Ray ComputedAdultAnkle InjuriesCase-Control StudiesFemaleHumansJoint DiseasesLateral Ligament, AnkleMaleNetherlandsPhysical ExaminationPrimary Health CareReproducibility of ResultsSprains and StrainsSurveys and Questionnairesabnormalitiesanklegeneral practiceimagingsprain

Identifiers

PMID25179068
PMCPMC4141611
OpenAlexW2079981012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.