Evidence map›Paper›PMID 25179036›Full record

Observational studyAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2014

Depressive symptoms and the relationship of inflammation to physical signs and symptoms in heart failure patients.

Seongkum Heo, Debra K Moser, Susan J Pressler, Sandra B Dunbar, Rebecca L Dekker, Terry A Lennie

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Seongkum HeoSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia. sheo@uams.edu.
Debra K MoserSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia.
Susan J PresslerSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia.
Sandra B DunbarSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia.
Rebecca L DekkerSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia.
Terry A LennieSeongkum Heo is an assistant professor, University of Arkansas for Medical Sciences, College of Nursing, Little Rock, Arkansas. Debra K. Moser is a professor and Gill Chair of Nursing, Rebecca L. Dekker is an assistant professor, and Terry A. Lennie is a professor, University of Kentucky, College of Nursing, Lexington, Kentucky. Susan J. Pressler is a professor, University of Michigan, School of Nursing, Ann Arbor, Michigan, and Sandra B. Dunbar is a professor, Emory University, School of Nursing, Atlanta, Georgia.
University of Arkansas for Medical Sciences · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
BMI, Nutrition, Inflammation and Heart Failure OutcomesR01NR009280 · NINR · UNIVERSITY OF KENTUCKY · PI LENNIE, TERRY A · 2005 to 2007
$1.5M
Self-Management Pilot/Feasibility and Biobehavioral Outcomes CoreP20NR010679 · NINR · UNIVERSITY OF KENTUCKY · PI MOSER, DEBRA KAY · 2007 to 2011
$1.2M
Cognitive Therapy for Depressive Symptoms in Hospitalized Patients with Heart FaiK23NR013480 · NINR · UNIVERSITY OF KENTUCKY · PI DEKKER, REBECCA · 2012 to 2014
$356k
NCATS NIH HHS UL1 TR000454NCRR NIH HHS M01 RR000039NCRR NIH HHS M01 RR0039NCRR NIH HHS UL1 RR025008NINR NIH HHS 1P20NR010679NINR NIH HHS K23 NR013480NINR NIH HHS P20 NR010679NINR NIH HHS R01 NR009280
6 · The paper itself

Abstract

backgroundDepressive symptoms in patients with heart failure can affect the relationship between physical signs and symptoms and inflammation.

objectiveTo examine the relationship between soluble tumor necrosis factor receptor I and physical signs and symptoms and the effects of depressive symptoms on this relationship in patients with heart failure.

methodsData on physical signs and symptoms (Symptom Status Questionnaire-Heart Failure), depressive symptoms (Beck Depression Inventory-II), and levels of the receptor (blood samples) were collected from 145 patients with heart failure. Data on the receptor were square root transformed to achieve normality. Patients were divided into 2 groups according to their scores for depressive symptoms (nondepressed <14 and depressed ≥14). Hierarchical multiple regression was used to analyze the data.

resultsIn the total sample, with controls for covariates, higher levels of the receptor were significantly related to more severe physical signs and symptoms (F = 7.915; P < .001). In subgroup analyses, with controls for covariates, levels of the receptor were significantly related to physical signs and symptoms only in the patients without depression (F = 3.174; P = .005).

conclusionBoth depressive symptoms and inflammation should be considered along with physical signs and symptoms in patients with heart failure. Further studies are needed to determine the effects of improvement in inflammation on improvement in physical signs and symptoms, with consideration given to the effects of depressive symptoms.

Indexed as

AgedBody Mass IndexComorbidityDepressionDyspneaEdemaFatigueFemaleHeart FailureHumansInflammationMaleMiddle AgedProspective StudiesPsychiatric Status Rating ScalesReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type I

Identifiers

PMID25179036
PMCPMC4155761
OpenAlexW2160488285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.