ArticleBehavioral and brain functions : BBF2014
Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population.
Article in Behavioral and brain functions : BBF, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- The effect of reading problems on emotional and behavioral problems in children: the chain mediating role of parenting stress and parental anxiety/depressive symptoms.BMC psychiatry · 2026Article
- Development and Validity of the Adult Reading History Questionnaire (ARHQ) for Chinese.Dyslexia (Chichester, England) · 2025Article
- A Biopsychosocial Overview of Speech Disorders: Neuroanatomical, Genetic, and Environmental Insights.Biomedicines · 2025Review
- Association between dyslexia and overweight/obesity among Chinese children: findings from a cross-sectional study.Frontiers in pediatrics · 2025Article
- Dyslexia and Stuttering: An Overview of Processing Deficits and the Relationship Between Them.Cureus · 2023Review
- Associative gene networks reveal novel candidates important for ADHD and dyslexia comorbidity.BMC medical genomics · 2023Article
- Stuttering as a spectrum disorder: A hypothesis.Current research in neurobiology · 2023Review
- Article
- Neurofilament-lysosomal genetic intersections in the cortical network of stuttering.Progress in neurobiology · 2020Article
- The Pharmacologic Treatment of Stuttering and Its Neuropharmacologic Basis.Frontiers in neuroscience · 2020Review
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyslexia is a polygenic developmental disorder characterized by difficulties in reading and spelling despite normal intelligence, educational backgrounds and perception. Increasing evidences indicated that dyslexia may share similar genetic mechanisms with other speech and language disorders. We proposed that stuttering candidate genes, DRD2 and SLC6A3, might be associated with dyslexia. METHODS AND
resultsThe study was conducted in an unrelated Chinese cohort with 502 dyslexic cases and 522 healthy controls. In total, 23 Tag SNPs covering the two genes were selected for genotyping through Tagger program. Association analysis was performed on each SNP alone and in haplotypes. One SNP markers in DRD2 showed significant association with developmental dyslexia.
conclusionThese findings indicate that polymorphism of DRD2 gene may be a risk factor of developmental dyslexia in the Chinese population.
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