Evidence map›Paper›PMID 25178910›Full record

ArticleChemical communications (Cambridge, England)2014

Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols.

Hui Li, Xiaoxun Li, Hao-Yuan Wang, Gabrielle N Winston-McPherson, Hao-miao Julie Geng, Ilia A Guzei, Weiping Tang

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.Angewandte Chemie (International ed. in English) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui LiSchool of Pharmacy, University of Wisconsin, Madison, WI 53705, USA. wtang@pharmacy.wisc.edu.
Xiaoxun Li
Hao-Yuan Wang
Gabrielle N Winston-McPherson
Hao-miao Julie Geng
Ilia A Guzei
Weiping Tang

Funding

Development of Cyclopropyl Metal Carbene Based Methods for Organic SynthesisR01GM088285 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI TANG, WEIPING · 2009 to 2013
$1.5M
NIGMS NIH HHS R01 GM088285NIGMS NIH HHS R01GM088285
6 · The paper itself

Abstract

Various highly substituted 2,3'-diindolylmethane heterocycles were prepared from propargylic alcohols and indole nucleophiles via a transition metal-catalyzed tandem indole annulation/arylation reaction for the first time. Among the metal catalysts we examined, the most economical copper(I) catalyst provided the highest efficiency. The indole nucleophiles could also be replaced by other electron-rich arenes or alcohols.

Indexed as

AlkynesCatalysisCopperIndolesPropanols3,3'-diindolylmethaneAlkynesCopperIndolesPropanolspropargyl alcohol

Identifiers

PMID25178910
PMCPMC4169321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.