Evidence map›Paper›PMID 25178894›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2014

Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging.

Hongmin Chen, Geoffrey D Wang, Wei Tang, Trever Todd, Zipeng Zhen, Chu Tsang, Khan Hekmatyar, Taku Cowger, Richard Hubbard, Weizhong Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Targeted nanotherapy for kidney diseases: a comprehensive review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Review
  7. Article
  8. Synthesis and characterization of GdScientific reports · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hongmin Chen *Department of Chemistry, The University of Georgia, Athens, Georgia 30602, USA; Department of Radiology and Molecular Imaging Center, The Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P. R. China.
Geoffrey D Wang *Department of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Wei TangDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Trever ToddDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Zipeng ZhenDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Chu TsangDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Khan HekmatyarBio-Imaging Research Center, The University of Georgia, Athens, Georgia 30602, USA.
Taku CowgerDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Richard HubbardDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Weizhong ZhangDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
John StickneyDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA.
Baozhong ShenDepartment of Radiology and Molecular Imaging Center, The Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P. R. China.
Jin XieDepartment of Chemistry, The University of Georgia, Athens, Georgia 30602, USA; Bio-Imaging Research Center, The University of Georgia, Athens, Georgia 30602, USA.

Funding

Nanoplatform-based combinational therapy against breast cancer R00CA153772 · NCI · UNIVERSITY OF GEORGIA · PI XIE, JIN · 2011 to 2013
$710k
NCI NIH HHS 5R00CA153772NCI NIH HHS R00 CA153772
6 · The paper itself

Abstract

Nanoprobes for MRI and optical imaging are demonstrated. Gd@C-dots possess strong fluorescence and can effectively enhance signals on T1 -weighted MR images. The nanoprobes have low toxicity, and, despite a relatively large size, can be efficiently excreted by renal clearance from the host after systemic injection.

Indexed as

AnimalsCapsulesCarbonCell Line, TumorCell SurvivalContrast MediaDrug StabilityGadoliniumHumansKidneyLigandsMagnetic Resonance ImagingMiceNanoparticlesOligopeptidesarginyl-glycyl-aspartic acidCapsulesCarbonContrast MediaGadoliniumLigandsOligopeptidescarbonaceous dotsgadoliniumMRIrenal clearanceT1 contrast agent

Identifiers

PMID25178894
PMCPMC4885638

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.