Evidence map›Paper›PMID 25178285›Full record

ArticleSexually transmitted infections2014

Modest rise in chlamydia and gonorrhoea testing did not increase case detection in a clinical HIV cohort in Ontario, Canada.

Ann N Burchell, Ramandip Grewal, Vanessa G Allen, Sandra L Gardner, Veronika Moravan, Ahmed M Bayoumi, Rupert Kaul, Frank McGee, Margaret Peggy E Millson, Robert S Remis and 4 more

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
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  4. Chlamydia and Gonorrhea Incidence and Testing Among Patients in the Human Immunodeficiency Virus Outpatient Study (HOPS), 2007-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ann N BurchellOntario HIV Treatment Network, Toronto, Ontario, Canada Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Ramandip GrewalOntario HIV Treatment Network, Toronto, Ontario, Canada.
Vanessa G AllenPublic Health Laboratories, Public Health Ontario, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Sandra L GardnerOntario HIV Treatment Network, Toronto, Ontario, Canada Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Veronika MoravanOntario HIV Treatment Network, Toronto, Ontario, Canada.
Ahmed M BayoumiDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Centre for Research on Inner City Health, The Keenan Research Centre in the Li KaShing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Rupert KaulDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Frank McGeeAIDS Bureau, Ontario Ministry of Health and Long Term Care, Toronto, Ontario, Canada.
Margaret Peggy E MillsonDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Robert S RemisDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Janet RaboudDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.
Tony MazzulliPublic Health Laboratories, Public Health Ontario, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada Mount Sinai Hospital/University Health Network, Toronto, Ontario, Canada.
Sean B RourkeOntario HIV Treatment Network, Toronto, Ontario, Canada Centre for Research on Inner City Health, The Keenan Research Centre in the Li KaShing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
OHTN Cohort Study Team

Funding

Canadian Institutes of Health Research 111146
6 · The paper itself

Abstract

objectivesWe described patterns of testing for chlamydia and gonorrhoea infection among persons in specialty HIV care in Ontario, Canada, from 2008 to 2011.

methodsWe analysed data from 3165 participants in the OHTN Cohort Study attending one of seven specialty HIV care clinics. We obtained chlamydia and gonorrhoea test results via record linkage with the provincial public health laboratory. We estimated the proportion of participants who underwent testing annually, the positivity rate among those tested and the proportion diagnosed with chlamydia or gonorrhoea among all under observation. We explored risk factors for testing and diagnosis using multiple logistic regression analysis.

resultsThe proportion tested annually rose from 15.2% (95% CI 13.6% to 16.7%) in 2008 to 27.0% (95% CI 25.3% to 28.6%) in 2011 (p<0.0001). Virtually all were urine-based nucleic acid amplification tests. Testing was more common among men who have sex with men (MSM), younger adults, Toronto residents, persons attending primary care clinics and persons who had tested in the previous year or who had more clinic visits in the current year. We observed a decrease in test positivity rates over time. However, the annual proportion diagnosed remained stable and in 2011 this was 0.97% (95% CI 0.61% to 1.3%) and 0.79% (95% CI 0.46% to 1.1%) for chlamydia and gonorrhoea, respectively. Virtually all cases were among MSM.

conclusionsChlamydia and gonorrhoea testing increased over time while test positivity rates declined and the overall proportion diagnosed remained stable, suggesting that the modest increase in testing did not improve case detection.

Indexed as

AdultChlamydia InfectionsCohort StudiesFemaleGonorrheaHIV InfectionsHumansMaleMiddle AgedOntarioPrevalenceCHLAMYDIA INFECTIONGAY MENGONORRHOEAHIVSCREENING

Identifiers

PMID25178285
PMCPMC4251188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.