Evidence map›Paper›PMID 25178013›Full record

ArticleJournal of synchrotron radiation2014

X-ray micro-diffraction studies on biological samples at the BioCAT Beamline 18-ID at the Advanced Photon Source.

R A Barrea, O Antipova, D Gore, R Heurich, M Vukonich, N G Kujala, T C Irving, J P R O Orgel

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R A BarreaThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
O AntipovaThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
D GoreThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
R HeurichThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
M VukonichThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
N G KujalaThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
T C IrvingThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
J P R O OrgelThe Biophysics Collaborative Access Team (BioCAT), CSRRI and Departments of Biology, Physics and Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.

Funding

Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
NIGMS NIH HHS 9 P41 GM103622-18NIGMS NIH HHS P41 GM103622
6 · The paper itself

Abstract

The small source sizes of third-generation synchrotron sources are ideal for the production of microbeams for diffraction studies of crystalline and non-crystalline materials. While several such facilities have been available around the world for some time now, few have been optimized for the handling of delicate soft-tissue specimens under cryogenic conditions. Here the development of a new X-ray micro-diffraction instrument at the Biophysics Collaborative Access Team beamline 18-ID at the Advanced Photon Source, and its use with newly developed cryo-diffraction techniques for soft-tissue studies, are described. The combination of the small beam sizes delivered by this instrument, the high delivered flux and successful cryo-freezing of rat-tail tendon has enabled us to record data to better than 4 Å resolution. The ability to quickly raster scan samples in the beam allows selection of ordered regions in fibrous samples for markedly improved data quality. Examples of results of experiments obtainable using this instrument are presented.

Indexed as

Alzheimer DiseaseAnimalsCollagenCrystallography, X-RayEquipment DesignHumansIllinoisLampreysNotochordPhotonsRadiographyRatsSpectrometry, X-Ray EmissionSynchrotronsTendonsX-Ray DiffractionCollagenamyloidbiological samplescollagenmicrofocusX-ray diffraction

Identifiers

PMID25178013
PMCPMC4151685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.