Evidence map›Paper›PMID 25177992›Full record

ArticleJournal of synchrotron radiation2014

X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens.

Martin D de Jonge, Christopher G Ryan, Chris J Jacobsen

Abstract read
In one paragraph

Article in Journal of synchrotron radiation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Hard X-ray Nanoprobe beamline at Diamond Light Source.Journal of synchrotron radiation · 2021
    Article
  7. Article
  8. Simulated sample heating from a nanofocused X-ray beam.Journal of synchrotron radiation · 2017
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Martin D de JongeAustralian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168, Australia.
Christopher G RyanCSIRO Earth Science and Research Engineering, Clayton, Victoria 3168, Australia.
Chris J JacobsenAdvanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439, USA.

Funding

Cryo ptychography combined with x-ray fluorescence analysis of metals in cellsR01GM104530 · NIGMS · NORTHWESTERN UNIVERSITY · PI JACOBSEN, CHRIS JOHNSON · 2013 to 2020
$2.2M
NIGMS NIH HHS R01 GM104530NIGMS NIH HHS R01GM-104530
6 · The paper itself

Abstract

X-ray nanoprobes require coherent illumination to achieve optic-limited resolution, and so will benefit directly from diffraction-limited storage rings. Here, the example of high-resolution X-ray fluorescence tomography is focused on as one of the most voracious demanders of coherent photons, since the detected signal is only a small fraction of the incident flux. Alternative schemes are considered for beam delivery, sample scanning and detectors. One must consider as well the steps before and after the X-ray experiment: sample preparation and examination conditions, and analysis complexity due to minimum dose requirements and self-absorption. By understanding the requirements and opportunities for nanoscale fluorescence tomography, one gains insight into the R&D challenges in optics and instrumentation needed to fully exploit the source advances that diffraction-limited storage rings offer.

Indexed as

Microscopy, FluorescenceImage EnhancementMolecular Probe TechniquesNanoparticlesOptics and PhotonicsRadiation DosageSynchrotronsX-Ray DiffractionX-Ray Microtomographydiffraction-limited storage ringsfluorescence tomographynanotomographyscanning X-ray microscopyX-ray fluorescence microscopy

Identifiers

PMID25177992
PMCPMC4151681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.