ArticleBioMed research international2014
Impact of seasons and dioecy on therapeutic phytoconstituents of Tinospora cordifolia, a Rasayana drug.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Exploring the Medicinal and Nutraceutical Frontiers ofCurrent topics in medicinal chemistry · 2025Review
- Phytochemical analysis ofWorld journal of experimental medicine · 2024Review
- Tinosporaside fromMolecules (Basel, Switzerland) · 2023Article
- Article
- Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.Medicinal research reviews · 2021Review
- Sexual Dimorphism in the Chemical Composition of Male and Female in the Dioecious Tree,International journal of molecular sciences · 2020Article
- Enhanced production of berberine in In vitro regenerated cell of Tinospora cordifolia and its analysis through LCMS QToF.3 Biotech · 2017Article
- Altitudinal variation of berberine, total phenolics and flavonoid content in Thalictrum foliolosum and their correlation with antimicrobial and antioxidant activities.Journal of Ayurveda and integrative medicineArticle
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Authors and funding
4 authors.
Funding
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Abstract
Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a dioecious creeper, commonly known as "Giloe" or "Guduchi" with significant medicinal importance in the traditional systems of medicine. It is designated as Rasayana drug in Ayurveda and recommended for a number of diseases and also as adaptogen and immunomodulator. The safety and efficacy of herbal medicines are closely correlated with the quality of the source materials. The aim of this study is to see the effect of seasons on phytoconstituents and how these vary in male and female stem samples of T. cordifolia. The study revealed that total phenolics and total sugar concentration obtained highest values in summer season while starch and tannin content were found maximum in winter season in both the genders. However, biomarkers, tinosporaside and berberine, reached to their highest concentration in monsoon season. Further, antioxidant potential revealed the highest inhibition percentage in winter season as well as in late summer season. The results of this study suggest that the female plant is best for its therapeutic phytoconstituents and the best harvesting seasons may be either winter or late summer for antioxidant potential and immunomodulator activities and monsoon for antidiabetic activity of T. cordifolia.
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