Evidence map›Paper›PMID 25177555›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Effect of yoga on oxidative stress in elderly with grade-I hypertension: a randomized controlled study.

Satish G Patil, Gopal B Dhanakshirur, Manjunatha R Aithala, Govindanagouda Naregal, Kusal K Das

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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  19. The Effects of Yoga in Patients Suffering from Subjective Tinnitus.International archives of otorhinolaryngology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Satish G PatilPhD Fellow, Department of Physiology, BLDE University's Shri B.M.Patil Medical College, Hospital & Research Centre , Karnataka, India .
Gopal B DhanakshirurProfessor, Department of Physiology, BLDE University's Shri B.M.Patil Medical College, Hospital & Research Centre , Karnataka, India .
Manjunatha R AithalaProfessor, Department of Physiology, BLDE University's Shri B.M.Patil Medical College, Hospital & Research Centre , Karnataka, India .
Govindanagouda NaregalPostgraudate, Department of Biochemistry, BLDE University's Shri B.M.Patil Medical College, Hospital & Research Centre , Karnataka, India .
Kusal K DasProfessor, Department of Physiology, BLDE University's Shri B.M.Patil Medical College, Hospital & Research Centre , Karnataka, India .
Shri BM Patil Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesHypertension, especially in elderly is a strong risk factor for cardiovascular mortality and morbidity. Oxidative stress has been implicated as one of the underlying cause of hypertension. Yoga has been found to control hypertension in the elderly, but the underlying benefits of mechanism in relation to oxidative stress regulation remains unclear. The purpose of the study was to investigate the effect of yoga on oxidative stress in elderly with Grade-I hypertension.

methodsAn open parallel-arm randomised controlled study was conducted at BLDE University's Shri B.M.Patil Medical College, Hospital and Research Centre, India on elderly male individuals with Grade-I hypertension (n=57, age 60-80 years). Study (Yoga) group was assigned for yoga intervention and control group for walking for one hour in the morning for six days in a week for three months under the supervision of yoga instructor and physical training instructor respectively. Serum malondialdehyde (MDA) as an indicator of oxidative stress and antioxidants such as serum superoxide dismutase (SOD), reduced glutathione (GSH) and vitamin C levels were estimated.

resultsYoga practice for three months has significantly reduced serum MDA level (p<0.001), and enhanced antioxidants level such as SOD activity (p=0.007), serum GSH (p=0.002) and vitamin C (p=0.002). In the control group, we observed a significant increase in serum MDA level (p=0.04) and reduction in serum vitamin C level (p=0.015) with no significant difference in the SOD activity and GSH level.

conclusionThese findings suggest that yoga is an effective means to reduce oxidative stress and to improve antioxidant defense in elderly hypertensive individuals.

Indexed as

AntioxidantsBrisk-walkElderlyHypertensionOxidative stressYoga

Identifiers

PMID25177555
PMCPMC4149061
OpenAlexW2127619552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.