ArticleBulletin of the World Health Organization2014
Varicella and herpes zoster hospitalizations before and after implementation of one-dose varicella vaccination in Australia: an ecological study.
Article in Bulletin of the World Health Organization, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- A systematic literature review of the epidemiology and burden of herpes zoster in selected locales in Asia Pacific.Human vaccines & immunotherapeutics · 2024Pooled it
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- Weighted ensemble learning outperforms statistical, machine-learning, and deep-learning models for varicella forecasting: a 12-model benchmarking study using 11-year surveillance data from Nanjing, China.Frontiers in public health · 2026Article
- Trends in age-specific varicella incidences following the introduction of the general recommendation for varicella immunization in Germany, 2006-2022.BMC public health · 2023Article
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- Epidemiology of Herpes Zoster in the pre-vaccination era: establishing the baseline for vaccination programme's impact in Spain.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Meningitis without Rash after Reactivation of Varicella Vaccine Strain in a 12-Year-Old Immunocompetent Boy.Vaccines · 2023Article
- Global varicella vaccination programs.Clinical and experimental pediatrics · 2022Article
- Cost effectiveness and budget impact of universal varicella vaccination in Russia.Human vaccines & immunotherapeutics · 2022Article
- Routine varicella vaccination program and hospitalization for herpes zoster in Japan.Human vaccines & immunotherapeutics · 2021Article
- Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data.BMJ (Clinical research ed.) · 2020Observational
- Spatiotemporal Epidemiology of Varicella in Chongqing, China, 2014-2018.International journal of environmental research and public health · 2020Article
- Specific Varicella-Related Complications and Their Decrease in Hospitalized Children after the Introduction of General Varicella Vaccination: Results from a Multicenter Pediatric Hospital Surveillance Study in Bavaria (Germany).Infectious diseases and therapy · 2019Article
- Burden of varicella complications in secondary care, England, 2004 to 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- The impact of childhood varicella vaccination on the incidence of herpes zoster in the general population: modelling the effect of exogenous and endogenous varicella-zoster virus immunity boosting.BMC infectious diseases · 2019Article
- Trends in varicella and herpes zoster epidemiology before and after the implementation of universal one-dose varicella vaccination over one decade in South Korea, 2003-2015.Human vaccines & immunotherapeutics · 2019Article
- Global impact of varicella vaccination programs.Human vaccines & immunotherapeutics · 2019Review
- A national register-based study of paediatric varicella hospitalizations in Denmark 2010-2016.Epidemiology and infection · 2017Article
- Evaluation of Combination Measles-Mumps-Rubella-Varicella Vaccine Introduction in Australia.JAMA pediatrics · 2017Article
- Varicella vaccination - the global experience.Expert review of vaccines · 2017Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine trends in varicella and herpes zoster (HZ) hospitalization following the availability and subsequent National Immunization Programme funding of one-dose varicella vaccination in Australia.
methodsVaricella vaccination coverage for children born between 2001 and 2009 was obtained from the Australian Childhood Immunization Register. Principal or any coded varicella or HZ hospitalizations were retrieved from the national hospital morbidity database from 1998 to 2010. Trends in hospitalization rates in different age groups and indigenous status were assessed. Incidence rate ratios (IRR) were calculated between periods before and after implementation of immunization programme funding.
findingsIn the first year of the funded immunization programme, varicella vaccine coverage reached 75% in children aged 24 months and more than 80% in children aged 60 months. Compared with the pre-vaccine period, varicella hospitalization rates during the funded programme were significantly lower for age groups younger than 40 years; with the greatest reduction in children aged 18-59 months (IRR: 0.25; 95% confidence interval, CI: 0.22-0.29). Indigenous children had a higher varicella hospitalization rate compared with non-indigenous children before vaccine implementation (IRR: 1.9; 95% CI: 1.4-2.7), but afterwards reached equivalence (IRR: 1.1; 95% CI: 0.7-1.6). The age-standardized HZ hospitalization rate declined between the periods (IRR: 0.95; 95% CI: 0.92-0.97).
conclusionRapid attainment of high coverage reduced varicella hospitalizations in the targeted age group, particularly for indigenous children, but also in non-targeted age groups, with no increase in HZ hospitalizations. This suggests high one-dose varicella vaccine coverage can have a substantial impact on severe disease.
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