ArticleComprehensive psychiatry2014
Seasonal variation of depressive symptoms in unipolar major depressive disorder.
Article in Comprehensive psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seasonality and symptoms of depression: A systematic review of the literature.Epidemiology and psychiatric sciences · 2019Pooled it
- Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- Fasting ghrelin as mediator between obesity and depressive symptoms: a pre-registered study.Npj mental health research · 2026Article
- Psychological distress among healthcare providers during the COVID-19 pandemic: patterns over time.BMC health services research · 2024Article
- Evening Chronotype and Suicide: Exploring Neuroinflammation and Psychopathological Dimensions as Possible Bridging Factors-A Narrative Review.Brain sciences · 2023Review
- The role of sleep quality and perceived stress on depressive symptoms among tertiary hospital nurses: a cross-sectional study.BMC psychiatry · 2023Article
- Seasonal sensitivity and psychiatric morbidity: study about seasonal affective disorder.BMC psychiatry · 2021Article
- Impact of seasons on stroke-related depression, mediated by vitamin D status.BMC psychiatry · 2018Article
- Seasonal variation in major depressive episode prevalence in Canada.Epidemiology and psychiatric sciences · 2017Article
- Pupillary response abnormalities in depressive disorders.Psychiatry research · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesRetrospective and cross-sectional studies of seasonal variation of depressive symptoms in unipolar major depression have yielded conflicting results. We examined seasonal variation of mood symptoms in a long-term prospective cohort - the Collaborative Depression Study (CDS).
methodsThe sample included 298 CDS participants from five academic centers with a prospectively derived diagnosis of unipolar major depression who were followed for at least ten years of annual or semi-annual assessments. Generalized linear mixed models were utilized to investigate the presence of seasonal patterns. In a subset of 271 participants followed for at least 20 years, the stability of a winter depressive pattern was assessed across the first two decades of follow-up.
resultsA small increase in proportion of time depressed was found in the months surrounding the winter solstice, although the greatest symptom burden was seen in December through April with a peak in March. The relative burden of winter depressive symptoms in the first decade demonstrated no relationship to that of the second decade. The onset of new episodes was highest October through January, peaking in January.
conclusionsThere exists a small but statistically significant peak in depressive symptoms from the month of the winter solstice to the month of the spring equinox. However, the predominance of winter depressive symptoms did not appear stable over the long-term course of illness.
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