ReviewCell metabolism2014
Mapping the inner workings of the microbiome: genomic- and metagenomic-based study of metabolism and metabolic interactions in the human microbiome.
Review in Cell metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses.Nature communications · 2026Article
- The Gut Microbiome and Its Impact on Mood and Decision-Making: A Mechanistic and Therapeutic Review.Nutrients · 2025Review
- Gut microbial GABA imbalance emerges as a metabolic signature in mild autism spectrum disorder linked to overrepresented Escherichia.Cell reports. Medicine · 2025Article
- Integrating the milk microbiome signatures in mastitis: milk-omics and functional implications.World journal of microbiology & biotechnology · 2025Review
- Article
- Challenges for pathologists in implementing clinical microbiome diagnostic testing.The journal of pathology. Clinical research · 2024Review
- Emerging tools and best practices for studying gut microbial community metabolism.Nature metabolism · 2024Review
- Attention Deficit Hyperactivity Disorder (ADHD) and the gut microbiome: An ecological perspective.PloS one · 2023Article
- The Microbial and Metabolic Signatures of Patients with Stable Coronary Artery Disease.Microbiology spectrum · 2022Article
- Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics.Computational and structural biotechnology journal · 2022Review
- A compendium of predicted growths and derived symbiotic relationships between 803 gut microbes in 13 different diets.Current research in microbial sciences · 2022Article
- A quasi-paired cohort strategy reveals the impaired detoxifying function of microbes in the gut of autistic children.Science advances · 2020Article
- Contrasting Strategies: Human Eukaryotic Versus Bacterial Microbiome Research.The Journal of eukaryotic microbiology · 2020Review
- Computational Modeling of the Human Microbiome.Microorganisms · 2020Review
- Opportunities at the Interface of Network Science and Metabolic Modeling.Frontiers in bioengineering and biotechnology · 2020Review
- Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.Frontiers in neuroscience · 2020Review
- Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies.mSystems · 2019Article
- Biological Contamination Prevention for Outer Solar System Moons of Astrobiological Interest: What Do We Need to Know?Astrobiology · 2019Article
- Establishment and evaluation of prediction model for multiple disease classification based on gut microbial data.Scientific reports · 2019Article
- Lung inflammation and disease: A perspective on microbial homeostasis and metabolism.IUBMB life · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The human gut microbiome is a major contributor to human metabolism and health, yet the metabolic processes that are carried out by various community members, the way these members interact with each other and with the host, and the impact of such interactions on the overall metabolic machinery of the microbiome have not yet been mapped. Here, we discuss recent efforts to study the metabolic inner workings of this complex ecosystem. We will specifically highlight two interrelated lines of work, the first aiming to deconvolve the microbiome and to characterize the metabolic capacity of various microbiome species and the second aiming to utilize computational modeling to infer and study metabolic interactions between these species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.