Evidence map›Paper›PMID 25175694›Full record

ReviewJournal of cardiac failure2014

Functional status in left ventricular assist device-supported patients: a literature review.

Martha Abshire, Cheryl R Dennison Himmelfarb, Stuart D Russell

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cardiac failure, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Martha AbshireJohns Hopkins University School of Nursing, Baltimore, Maryland. Electronic address: mabshir1@jhu.edu.
Cheryl R Dennison HimmelfarbJohns Hopkins University School of Nursing, Baltimore, Maryland; Johns Hopkins University School of Medicine, Baltimore, Maryland.
Stuart D RussellJohns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Institute for Clinical and Translational ResearchTL1TR001078 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$1.9M
Interdisciplinary Training in Cardiovascular Health ResearchT32NR012704 · NINR · JOHNS HOPKINS UNIVERSITY · PI ALLEN, JERILYN K · 2011 to 2020
$1.8M
NCATS NIH HHS 5TL1TR001078-02NCATS NIH HHS TL1 TR001078NCATS NIH HHS UL1 TR001079NINR NIH HHS T32 NR 012704NINR NIH HHS T32 NR012704
6 · The paper itself

Abstract

The prevalence of advanced heart failure (HF) is increasing because of the aging population and improvements in HF management strategies. Left ventricular assist device (LVAD) technology and management continue to advance rapidly, and it is anticipated that the number of LVAD implants will increase. LVADs have been demonstrated to extend life and improve outcomes in patients with advanced HF. The purpose of this article is to review and synthesize the evidence on impact of LVAD therapy on functional status. Significant functional gains were demonstrated in patients supported by LVAD throughout the 1st year, with most improvement in distance walked and peak oxygen consumption demonstrated in the 1st 6 months. Interventions to enhance exercise performance have had inconsistent effects on functional status. Poor exercise performance was associated with increased risk of adverse events. Functional status improved with LVAD therapy, although performance remained substantially reduced compared with age-adjusted norms. There is tremendous need to enhance our understanding of factors influencing functional outcomes in this high-risk population.

Indexed as

Quality of LifeAgedAged, 80 and overAgingDisease-Free SurvivalExerciseExercise ToleranceFemaleHeart-Assist DevicesHeart FailureHemodynamicsHumansMaleOxygen ConsumptionPrognosisSurvival Analysisfunctional statusHeart-assist deviceleft ventricular assist deviceoutcomesquality of life

Identifiers

PMID25175694
PMCPMC4555868
OpenAlexW2021030143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.