ArticleEnvironmental science and pollution research international2014
Influence of sediment composition on PAH toxicity using zebrafish (Danio rerio) and Japanese medaka (Oryzias latipes) embryo-larval assays.
Article in Environmental science and pollution research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Evolutionary toxicology: Meta-analysis of evolutionary events in response to chemical stressors.Ecotoxicology (London, England) · 2016Pooled it
- Oxygenated PAHs in Tokyo Bay sediments: distributional contrast with parent PAHs and their effect evaluations with fish embryos.Environmental monitoring and assessment · 2026Article
- Exposure to four chemical UV filters through contaminated sediment: impact on survival, hatching success, cardiac frequency, and aerobic metabolic scope in embryo-larval stage of zebrafish.Environmental science and pollution research international · 2021Article
- The importance of sediments in ecological quality assessment of stream headwaters: embryotoxicity along the Nidda River and its tributaries in Central Hesse, Germany.Environmental sciences Europe · 2018Article
- Early life co-exposures to a real-world PAH mixture and hypoxia result in later life and next generation consequences in medaka (Oryzias latipes).Aquatic toxicology (Amsterdam, Netherlands) · 2017Article
- Source apportionment of polycyclic aromatic hydrocarbons and n-alkanes in the soil-sediment profile of Jianghan Oil Field, China.Environmental science and pollution research international · 2017Article
- Water quality assessment in the "German River of the years 2014/2015": how a case study on the impact of a storm water sedimentation basin displayed impairment of fish health in the Argen River (Southern Germany).Environmental sciences Europe · 2017Article
- Acute and short-term developmental toxicity of cyhalofop-butyl to zebrafish (Danio rerio).Environmental science and pollution research international · 2016Article
- BioluminescentFrontiers in microbiology · 2016Article
- Embryonic exposure to benzo[a]pyrene causes age-dependent behavioral alterations and long-term metabolic dysfunction in zebrafish.Neurotoxicology and teratologyArticle
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to hydrophobic and persistent properties, polycyclic aromatic hydrocarbons (PAHs) have a high capacity to accumulate in sediment. Sediment quality criteria, for the assessment of habitat quality and risk for aquatic life, include understanding the fate and effects of PAHs. In the context of European regulation (REACH and Water Framework Directive), the first objective was to assess the influence of sediment composition on the toxicity of two model PAHs, benzo[a]pyrene and fluoranthene using 10-day zebrafish embryo-larval assay. This procedure was undertaken with an artificial sediment in order to limit natural sediment variability. A suitable sediment composition might be then validated for zebrafish and proposed in a new OECD guideline for chemicals testing. Second, a comparative study of toxicity responses from this exposure protocol was then performed using another OECD species, the Japanese medaka. The potential toxicity of both PAHs was assessed through lethal (e.g., survival, hatching success) and sublethal endpoints (e.g., abnormalities, PMR, and EROD) measured at different developmental stages, adapted to the embryonic development time of both species. Regarding effects observed for both species, a suitable artificial sediment composition for PAH toxicity testing was set at 92.5 % dry weight (dw) silica of 0.2-0.5-mm grain size, 5 % dw kaolin clay without organic matter for zebrafish, and 2.5 % dw blond peat in more only for Japanese medaka. PAH bioavailability and toxicity were highly dependent on the fraction of organic matter in sediment and of the K ow coefficients of the tested compounds. The biological responses observed were also dependent of the species under consideration. Japanese medaka embryos appeared more robust than zebrafish embryos for understanding the toxicity of PAHs following a sediment contact test, due to the longer exposure duration and lower sensitivity of sediment physical properties.
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