Evidence map›Paper›PMID 25174325›Full record

ArticleEuropean urology2015

The Evolution of Self-Reported Urinary and Sexual Dysfunction over the Last Two Decades: Implications for Comparative Effectiveness Research.

Matthew J Resnick, Daniel A Barocas, Alicia K Morgans, Sharon E Phillips, Tatsuki Koyama, Peter C Albertsen, Matthew R Cooperberg, Michael Goodman, Sheldon Greenfield, Ann S Hamilton and 9 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04884945 (Pediatric Robotic Versus Open Pyeloplasty), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04884945 naterminatednot on this mapstarted 2017, after this paper: background citation

Pediatric Robotic Versus Open Pyeloplasty: A Pilot Randomized Control Study

TypeinterventionalSponsorIndiana UniversityRan2017 to 2021Enrolled11ConditionsPediatric Urology, Ureteropelvic Junction ObstructionArmsOpen Pyeloplasty (OP), Robotic-Assisted Laparoscopic Pyeloplasty (RALP)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Matthew J ResnickDepartment of Urologic Surgery, Vanderbilt University, Nashville, TN, USA; Geriatric Research Education and Clinical Center, VA Tennessee Valley Healthcare System, Nashville, TN, USA. Electronic address: Matthew.Resnick@vanderbilt.edu.
Daniel A BarocasDepartment of Urologic Surgery, Vanderbilt University, Nashville, TN, USA.
Alicia K MorgansDepartment of Medicine, Vanderbilt University, Nashville, TN, USA.
Sharon E PhillipsDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Tatsuki KoyamaDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Peter C AlbertsenDivision of Urology, University of Connecticut Health Center, Farmington, CT, USA.
Matthew R CooperbergDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Michael GoodmanDepartment of Epidemiology, Emory University, Atlanta, GA, USA.
Sheldon GreenfieldDepartment of Medicine, University of California, Irvine, Irvine, CA, USA.
Ann S HamiltonDepartment of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Karen E HoffmanDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Richard M HoffmanDepartment of Medicine, University of New Mexico, Albuquerque, NM, USA.
Sherrie H KaplanDepartment of Medicine, University of California, Irvine, Irvine, CA, USA.
Dan McCollumEskind Biomedical Library, Vanderbilt University, Nashville, TN, USA.
Lisa E PaddockNew Jersey State Cancer Registry, Trenton, NJ, USA.
Janet L StanfordDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Antoinette M StroupNew Jersey State Cancer Registry, Trenton, NJ, USA.
Xiao-Cheng WuLouisiana State University Health Sciences Center, New Orleans, LA, USA.
David F PensonDepartment of Urologic Surgery, Vanderbilt University, Nashville, TN, USA; Geriatric Research Education and Clinical Center, VA Tennessee Valley Healthcare System, Nashville, TN, USA.

Funding

Comparative Effectiveness of Treatments for Localized Prostate CancerR01HS019356 · AHRQ · VANDERBILT UNIVERSITY · PI PENSON, DAVID F. · 2010 to 2010
$7.6M
The Vanderbilt PCOR Career Knowledge, Education and Training ProgramK12HS022990 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PENSON, DAVID F. · 2014 to 2018
$3.3M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067009 · PC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMAS, DAVID B · 1996 to 2000
$3.0M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067007 · PC · UNIVERSITY OF NEW MEXICO · PI KEY, CHARLES R · 1996 to 2000
$2.4M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067010 · PC · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROSS, RONALD K · 1996 to 2000
$2.4M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067005 · PC · CONNECTICUT STATE DEPT OF PUBLIC HEALTH · PI POLEDNAK, ANTHONY · 1996 to 2000
$1.9M
Comparative Effectiveness of Modern Therapies for Localized Prostate CancerR01HS022640 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PENSON, DAVID F. · 2013 to 2013
$1.8M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067006 · PC · EMORY UNIVERSITY · PI YOUNG, JOHN L · 1996 to 2000
$1.7M
Race, Comorbidity & Long Term Prostate Cancer OutcomesR01CA114524 · NCI · VANDERBILT UNIVERSITY · PI PENSON, DAVID F. · 2007 to 2009
$1.7M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067000 · PC · UNIVERSITY OF UTAH · PI WIGGINS, CHARLES L · 1996 to 2000
$1.3M
AHRQ HHS 1R01HS019356AHRQ HHS 1R01HS022640-01AHRQ HHS K12 HS022990AHRQ HHS R01 HS019356AHRQ HHS R01 HS022640NCI NIH HHS N01 PC067006NCI NIH HHS N01 PC067009NCI NIH HHS N01 PC067010NCI NIH HHS N01-PC-67000NCI NIH HHS N01-PC-67005NCI NIH HHS N01-PC-67006NCI NIH HHS N01-PC-67007NCI NIH HHS N01-PC-67009NCI NIH HHS R01 CA114524NCI NIH HHS R01-CA114524
6 · The paper itself

Abstract

backgroundDespite the paramount importance of patient-reported outcomes, little is known about the evolution of patient-reported urinary and sexual function over time.

objectiveTo evaluate differences in pretreatment urinary and sexual function in two population-based cohorts of men with prostate cancer enrolled nearly 20 yr apart. DESIGN, SETTING, AND

participantsPatients were enrolled in the Prostate Cancer Outcomes Study (PCOS) or the Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study, two population-based cohorts that enrolled patients with incident prostate cancer from 1994 to 1995 and from 2011 to 2012, respectively. Participants completed surveys at baseline and various time points thereafter. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: We performed multivariable logistic and linear regression analysis to investigate differences in pretreatment function between studies. RESULTS AND LIMITATIONS: The study comprised 5469 men of whom 2334 (43%) were enrolled in PCOS and 3135 (57%) were enrolled in CEASAR. Self-reported urinary incontinence was higher in CEASAR compared with PCOS (7.7% vs 4.7%; adjusted odds ratio [OR]: 1.83; 95% confidence interval [CI], 1.39-2.43). Similarly, self-reported erectile dysfunction was more common among CEASAR participants (44.7% vs 24.0%) with an adjusted OR of 3.12 (95% CI, 2.68-3.64). Multivariable linear regression models revealed less favorable self-reported baseline function among CEASAR participants in the urinary incontinence and sexual function domains. The study is limited by its observational design and possibility of unmeasured confounding.

conclusionsReporting of pretreatment urinary incontinence and erectile dysfunction has increased over the past two decades. These findings may reflect sociological changes including heightened media attention and direct-to-consumer marketing, among other potential explanations. PATIENT SUMMARY: Patient reporting of urinary and sexual function has evolved and is likely contingent on continually changing societal norms. Recognizing the evolving nature of patient reporting is essential in efforts to conduct high-quality, impactful comparative effectiveness research.

Indexed as

AdultAgedCohort StudiesComparative Effectiveness ResearchErectile DysfunctionHumansIncidenceMaleMiddle AgedProstatectomyProstatic NeoplasmsRadiotherapyRegression AnalysisRisk FactorsSelf ReportTime FactorsPatient-reported outcomesProstate cancerQuality of lifeSexual functionUrinary function

Identifiers

PMID25174325
PMCPMC4412750

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.