Evidence map›Paper›PMID 25174296›Full record

ArticleIl Giornale di chirurgia

From surgery to neurosurgery: our experience on the efficacy of fleece-bound sealing (TachoSil®) for dural repair.

S Ulivieri, G Peri, G Tiezzi, E Mileo, A Giorgio, G Oliveri

Abstract readCase Reports
In one paragraph

Article in Il Giornale di chirurgia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S Ulivieri
G Peri
G Tiezzi
E Mileo
A Giorgio
G Oliveri

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo report on our routine use of TachoSil® for dural repair in neurosurgical practice.

methodTachoSil® has been applied in different fields of surgery thus far. When using TachoSil®, fibrinogen and thrombin is provided locally at the site of the dural defects. Upon contact with fluid, the clotting factors of TachoSil® dissolve and form a fibrin network, which glues the collagen sponge to the wound surface.

resultsIn our experience, TachoSil® was found to be effective as support for the suture of the dura in patients undergoing spinal and cranial neurosurgical operations. Two illustrative examples are shown.

conclusionsOur procedure showed that closing the dural defect with TachoSil® is a technically simple, reliable and safe method for patients. Indeed, no post-operative cerebrospinal fluid leakage was observed. Nonetheless, further studies with larger sample size are warranted to confirm the efficacy of TachoSil® patches for dural repair.

Indexed as

FibrinogenNeurosurgical ProceduresThrombinAgedBrain IschemiaDrug CombinationsDura MaterFemaleHumansMaleMeningeal NeoplasmsMeningiomaMiddle AgedWound HealingDrug CombinationsFibrinogenTachoSilThrombin

Identifiers

PMID25174296
PMCPMC4321528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.