Evidence map›Paper›PMID 25173641›Full record

ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014

Long non-coding RNAs: emerging players in gastric cancer.

Xiaoqiang Guo, Jiazeng Xia, Kaiyuan Deng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Epigenetic reprogramming in cancer: From diagnosis to treatment.Frontiers in cell and developmental biology · 2023
    Review
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  19. Long noncoding RNA BCAR4 promotes osteosarcoma progression through activating GLI2-dependent gene transcription.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiaoqiang GuoDepartment of General Surgery and Translational Medicine Center, Nanjing Medical University Affiliated Wuxi Second Hospital, Wuxi, 214002, Jiangsu, China.
Jiazeng Xia
Kaiyuan Deng
Shanxi Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) remains a major public health issue as the second leading cause of cancer-related death and the fourth most common cancer worldwide. Although much progress has been achieved in recent years, the early diagnosis and treatment for GC are not yet satisfactory; thus, the prognosis remains poor. Therefore, identification of novel molecules for early diagnosis, prognosis, and treatment is urgently needed. Long non-coding RNAs (lncRNAs) are a new class of non-coding RNAs that participate in a variety of biological processes such as cell proliferation, cell cycle, differentiation, and apoptosis, mainly by regulation of gene expression at various levels, including chromatin, splicing, transcriptional, and post-transcriptional levels. Some lncRNAs are upregulated in cancer and possess oncogenic properties, while others exhibit aberrant low expression and act as tumor suppressors. In this review, we overview the functional roles and regulatory mechanisms of lncRNAs in GC and evaluate their diagnostic, prognostic, and therapeutic values.

Indexed as

Gene Expression Regulation, NeoplasticAnimalsHumansRNA, Long NoncodingSignal TransductionStomach NeoplasmsRNA, Long Noncoding

Identifiers

PMID25173641
OpenAlexW1996982038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.